Tipping the scales: Peptide-dependent dysregulation of neural circuit dynamics in Alzheimer's disease
Abstract
© 2020 Elsevier Inc. Evidence indicates synergistic and antagonistic effects of Alzheimer disease (AD)-related peptides on neuronal circuit excitability. Here, Harris et al. discuss the mechanistic underpinnings and present a circuit-based framework of AD progression with novel prospects for diagnosis and therapy.
Journal details
Journal Neuron
Volume 107
Issue number 3
Pages 417-435
Available online
Publication date
Full text links
Publisher website (DOI) 10.1016/j.neuron.2020.06.005
Europe PubMed Central 32579881
Pubmed 32579881
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