Two negatives make a positive for insulin secretion and growth


The confusingly named growth-blocking peptides are nutrient-dependent adipokines that stimulate insulin secretion and boost growth in developing flies. In this issue of Developmental Cell, Meschi et al. (2018) show that these adipose tissue-derived factors regulate insulin secretion by silencing a pair of inhibitory neurons that synapse with insulin-producing cells.

Journal details

Volume 48
Issue number 1
Pages 11-12
Publication date

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