What´s new in WHO fifth edition - urinary tract

Abstract

The fifth edition of the WHO blue book on urologic tumors, specifically in the bladder chapter, represents a refinement and update in the classification of bladder tumors building on the aggregate major changes made in previous editions. Progress in the molecular underpinnings of urothelial tumors, particularly with promising stratifiers for more precision based treatment approaches have been made. Special attention has been paid to burning questions in bladder pathology, such as grading, heterogeneous lesions, inverted tumors and substaging. The concept of neuroendocrine tumors will be explained precisely.