Research case studies Explore a selection of reports that spotlight particular areas of research at the Crick over the past five years.
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Breadcrumb Research Research topics Click on a research topic to see the labs working in that field. In this sectionSecondary NavigationIn this section A-Z of research labs Platforms & facilities A-Z researchers Applying our research Research partnerships Animal research Topics Research case studies Publications Covid-19 response Minee Choi from the Gandhi and Patani Lab using a microscope in the Light Microscopy STP Toggle to view hero caption Research topics Biochemistry & Proteomics Using biochemical and proteomic approaches to understand the molecules and interactions underlying biological processes. Cell Biology Understanding how cells convert information in their genome into form and function, and how they respond to their environment. Cell Cycle & Chromosomes Chemical Biology & High Throughput Using chemical tools and techniques to investigate biological mechanisms, and screening large libraries to identify promising compounds. Computational & Systems Biology Analysing large datasets to answer biomedical questions, and using systems approaches and computer modelling to understand biological processes. Developmental Biology Understanding the processes through which cells become the right types of cell in the right place to form functioning organs. Ecology, Evolution & Ethology Applying thinking from ecology and evolution to biomedicine to learn how higher levels of biological organisation influence organisms, organs and cells. Gene Expression Understanding cell behaviour by investigating which genes are expressed and active at different times and locations, and in response to which signals. Genetics & Genomics Obtaining genomic sequences for organisms from microbes to humans to study biological mechanisms in health and disease. Genome Integrity & Repair Understanding the mechanisms by which cells maintain genome integrity to explore new approaches to diseases such as cancer. Human Biology & Physiology Using tissue and organ models, whole body and organ imaging, and human genome sequences to improve translational research and improve human health. Imaging Imaging molecules, cells and tissues at different scales and resolutions to learn about biological processes and pathways. Immunology Studying immune cells, the signalling pathways involved in inflammation and immune responses, and cancer immunology. Infectious disease Studying the growth, metabolism, pathogenicity and evolution of the viruses, bacteria and parasites that cause infectious diseases. Metabolism Studying the regulation of metabolism to understand metabolic disorders like diabetes and a range of other diseases including cancer. Microfabrication & Bioengineering Designing and making microscale devices to manipulate cells, tissues and biochemical reactions for precise and predictable investigations. Model organisms Using model organisms, from viruses, yeast and bacteria to mice, fish and rats, to study the biological processes involved in human health and disease. Neurosciences Understanding how neural circuits in the nervous system process information; respond to stimuli; and give rise to our actions and behaviour. Signalling & Oncogenes Studying cell signalling pathways, including those involving oncogenes, to understand immune responses, development, cancer and neuroscience. Stem Cells Understanding how stem cells produce, maintain and renew all the different cell types in the embryo and in adult organs to study development and disease. Structural Biology & Biophysics Determining the shape, structure and activity of large biomolecules to reveal how they carry out complex biological processes in our cells and tissues. Synthetic Biology Combining knowledge of biology with engineering principles to build new biological systems, or learn more about natural biological pathways. Tumour Biology Finding new ways to treat, diagnose and prevent cancer by understanding the mutations and complex genomic changes within tumours that drive it. Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Biochemistry & Proteomics Using biochemical and proteomic approaches to understand the molecules and interactions underlying biological processes.
Cell Biology Understanding how cells convert information in their genome into form and function, and how they respond to their environment.
Chemical Biology & High Throughput Using chemical tools and techniques to investigate biological mechanisms, and screening large libraries to identify promising compounds.
Computational & Systems Biology Analysing large datasets to answer biomedical questions, and using systems approaches and computer modelling to understand biological processes.
Developmental Biology Understanding the processes through which cells become the right types of cell in the right place to form functioning organs.
Ecology, Evolution & Ethology Applying thinking from ecology and evolution to biomedicine to learn how higher levels of biological organisation influence organisms, organs and cells.
Gene Expression Understanding cell behaviour by investigating which genes are expressed and active at different times and locations, and in response to which signals.
Genetics & Genomics Obtaining genomic sequences for organisms from microbes to humans to study biological mechanisms in health and disease.
Genome Integrity & Repair Understanding the mechanisms by which cells maintain genome integrity to explore new approaches to diseases such as cancer.
Human Biology & Physiology Using tissue and organ models, whole body and organ imaging, and human genome sequences to improve translational research and improve human health.
Imaging Imaging molecules, cells and tissues at different scales and resolutions to learn about biological processes and pathways.
Immunology Studying immune cells, the signalling pathways involved in inflammation and immune responses, and cancer immunology.
Infectious disease Studying the growth, metabolism, pathogenicity and evolution of the viruses, bacteria and parasites that cause infectious diseases.
Metabolism Studying the regulation of metabolism to understand metabolic disorders like diabetes and a range of other diseases including cancer.
Microfabrication & Bioengineering Designing and making microscale devices to manipulate cells, tissues and biochemical reactions for precise and predictable investigations.
Model organisms Using model organisms, from viruses, yeast and bacteria to mice, fish and rats, to study the biological processes involved in human health and disease.
Neurosciences Understanding how neural circuits in the nervous system process information; respond to stimuli; and give rise to our actions and behaviour.
Signalling & Oncogenes Studying cell signalling pathways, including those involving oncogenes, to understand immune responses, development, cancer and neuroscience.
Stem Cells Understanding how stem cells produce, maintain and renew all the different cell types in the embryo and in adult organs to study development and disease.
Structural Biology & Biophysics Determining the shape, structure and activity of large biomolecules to reveal how they carry out complex biological processes in our cells and tissues.
Synthetic Biology Combining knowledge of biology with engineering principles to build new biological systems, or learn more about natural biological pathways.
Tumour Biology Finding new ways to treat, diagnose and prevent cancer by understanding the mutations and complex genomic changes within tumours that drive it.
