Advanced Sequencing

The Advanced Sequencing Team at Crick provides high quality Next Generation Sequence (NGS) data from a state-of-the-art, multi-platform core facility. We offer complete project management, from initial project planning and submission with the researcher, through sample preparation and sequencing, and onward to data analysis, which can be performed by the Bioinformatics Team in Computational Biology (CB). 

The process is captured and tracked by a sophisticated Laboratory Management System (LIMS) that can provide checkpoint status reports and follow individual samples through the facility and on to analysis. 

Within the ASF we have expertise in a wide range of NGS applications including RNA-Seq, ChIP-Seq, single cell sequencing (Fluidigm), genomic sequencing and capture methods. We run multiple Illumina platforms as well as Ion Torrent. We also constantly evaluate new technologies and platforms, and automate some of the more laborious of sample prep methods, such as the enrichment protocols offered by Agilent and Illumina. We are happy to accept pre-made libraries as well as raw samples, all of which undergo an initial, as well as continuous, quality control assessment.