Cell Biology and Signalling Interest Group

Cell biology in its broadest sense aims to understand how a cell, the basic unit of life, converts information stored within its genome into form and function in both space and time.

Image of the Vaccinia Virus dispersing from its peri-nuclear site of assembly to the cell periphery.

This includes understanding not only the inner workings of individual cells but also how they use signal transduction pathways to react and respond to each other and their environment. To achieve this end is a formidable task, as the different systems and organelles of the cell comprise complex protein, lipid and nucleic acid assemblies that are dynamic and interdependent. Moreover, these assemblies, which also have emergent properties that cannot be predicted from the list of parts, depend on their environment as well as their chemical and physical properties.

Our ability to tackle the complexity of the cell at all scales has benefited greatly from improved imaging and computational approaches, which allow quantitative analysis of the dynamics and interactions of molecules and cells.

The Cell Biology and Signalling Interest Group will bring together scientists working on diverse biological systems, with many different complementary expertise who not only want to understand how these processes are regulated in normal healthy cells, but also the numerous pathological consequences that result when they are misregulated. 

For more information, or to be added to the Interest Group mailing list, please contact Helen Golding (helen.golding@crick.ac.uk).

Upcoming seminars

  • 10 January, 16:00 - Gillian Griffiths, Cambridge Institute for Medical Research, 'Membrane specialisation, actin regulators and super-killers: how T cells control secretion'
  • 15 January, 16:00 - Mary Munson, University of Massachusetts, 'Molecular architecture and function of the exocyst complex in vesicle trafficking'
  • 9 February, 12:00 - Michael Sixt, IST Austria,'TBC'
  • 12 February, 16:00 - Adrian Saurin, University of Dundee, 'How protein phosphorylation signals are regulated and why the textbooks are misleading'
  • 13 February, 12:00 - Franck Perez, Institut Curie, Paris, 'TBC'
  • 21 February, 16:00 - Anna Ahkmanova, Utrecht University, 'Regulation of cell polarity, migration and division by microtubule minus-end binding proteins'
  • 28 March, 16:00 - Ana-Maria Lennon-Duménil, Institut Curie, Paris, 'Immune cell migration: from micro-fluidics to tissue imaging