WHO Influenza Centre: Publications

  • Beer, K; Dai, M; Howell, S; Rijal, P; Townsend, AR; Lin, Y; Wharton, SA; Daniels, RS and McCauley, JW (2018)
    Characterization of neutralizing epitopes in antigenic site B of recently circulating influenza A(H3N2) viruses.
    Journal of General Virology [Epub ahead of print] PubMed abstract
  • Dunning, J; Blankley, S; Hoang, LT; Cox, M; Graham, CM; James, PL; Bloom, CI; Chaussabel, D; Banchereau, J; Brett, SJ; Moffatt, MF; O'Garra, A; Openshaw, PJM and MOSAIC investigators (2018)
    Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza.
    Nature Immunology 19, 625-635 PubMed abstract
  • Groves, HT; McDonald, JU; Langat, P; Kinnear, E; Kellam, P; McCauley, J; Ellis, J; Thompson, C; Elderfield, R; Parker, L; Barclay, W and Tregoning, JS (2018)
    Mouse models of influenza infection with circulating strains to test seasonal vaccine efficacy.
    Frontiers in Immunology 9, 126 PubMed abstract
  • Hay, AJ and McCauley, JW (2018)
    The Global Influenza Surveillance and Response System (GISRS) - a future perspective.
    Influenza and Other Respiratory Viruses [Epub ahead of print] PubMed abstract
  • Morris, DH; Gostic, KM; Pompei, S; Bedford, T; Łuksza, M; Neher, RA; Grenfell, BT; Lässig, M and McCauley, JW (2018)
    Predictive modeling of influenza shows the promise of applied evolutionary biology.
    Trends in Microbiology 26, 102-118 PubMed abstract
  • Benton, DJ; Wharton, SA; Martin, SR and McCauley, JW (2017)
    Role of neuraminidase in influenza A(H7N9) receptor binding.
    Journal of Virology 91, e02293-02216 PubMed abstract
  • Cole, SL; Dunning, J; Kok, WL; Benam, KH; Benlahrech, A; Repapi, E; Martinez, FO; Drumright, L; Powell, TJ; Bennett, M; Elderfield, R; Thomas, C; MOSAIC investigators; Dong, T; McCauley, J; Liew, FY; Taylor, S; Zambon, M; Barclay, W; Cerundolo, V; Openshaw, PJ; McMichael, AJ and Ho, L-P (2017)
    M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza.
    JCI Insight 2, e91868 PubMed abstract
  • Glatman-Freedman, A; Drori, Y; Beni, SA; Friedman, N; Pando, R; Sefty, H; Tal, I; McCauley, J; Rahav, G; Keller, N; Shohat, T; Mendelson, E; Hindiyeh, M and Mandelboim, M (2017)
    Genetic divergence of influenza A(H3N2) amino acid substitutions mark the beginning of the 2016-2017 winter season in Israel.
    Journal of Clinical Virology 93, 71-75 PubMed abstract
  • Gubareva, LV; Besselaar, TG; Daniels, RS; Fry, A; Gregory, V; Huang, W; Hurt, AC; Jorquera, PA; Lackenby, A; Leang, S-K; Lo, J; Pereyaslov, D; Rebelo-de-Andrade, H; Siqueira, MM; Takashita, E; Odagiri, T; Wang, D; Zhang, W and Meijer, A (2017)
    Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors, 2015-2016.
    Antiviral Research 146, 12-20 PubMed abstract
  • Hampson, A; Barr, I; Cox, N; Donis, RO; Hirve, S; Jernigan, D; Katz, J; McCauley, J; Motta, F; Odagiri, T; Tam, JS; Waddell, A; Webby, R; Ziegler, T and Zhang, W (2017)
    Improving the selection and development of influenza vaccine viruses - Report of a WHO informal consultation on improving influenza vaccine virus selection, Hong Kong SAR, China, 18-20 November 2015.
    Vaccine 35, 1104-1109 PubMed abstract
  • Korsun, N; Angelova, S; Gregory, V; Daniels, R; Georgieva, I and McCauley, J (2017)
    Antigenic and genetic characterization of influenza viruses circulating in Bulgaria during the 2015/2016 season.
    Infection, Genetics and Evolution 49, 241-250 PubMed abstract
  • Langat, P; Raghwani, J; Dudas, G; Bowden, TA; Edwards, S; Gall, A; Bedford, T; Rambaut, A; Daniels, R; Russell, C; Pybus, OG; McCauley, J; Kellam, P and Watson, SJ (2017)
    Genome-wide evolutionary dynamics of influenza B viruses on a global scale.
    PLOS Pathogens 13, e1006749 PubMed abstract
  • Le, TT; Chang, P; Benton, D; McCauley, JW; Iqbal, M and Cass, AEG (2017)
    Dual recognition element lateral flow assay toward multiplex strain specific influenza virus detection.
    Analytical Chemistry 89, 6781-6786 PubMed abstract
  • Lin, Y; Wharton, SA; Whittaker, L; Dai, M; Ermetal, B; Lo, J; Pontoriero, A; Baumeister, E; Daniels, RS and McCauley, JW (2017)
    The characteristics and antigenic properties of recently emerged subclade 3C.3a and 3C.2a human influenza A(H3N2) viruses passaged in MDCK cells.
    Influenza and Other Respiratory Viruses 11, 263-274 PubMed abstract
  • McCauley, JW (2017)
    Viruses: Model to accelerate epidemic responses.
    Nature 542, 414 PubMed abstract
  • Peacock, TP; Benton, DJ; Sadeyen, J-R; Chang, P; Sealy, JE; Bryant, JE; Martin, SR; Shelton, H; McCauley, JW; Barclay, WS and Iqbal, M (2017)
    Variability in H9N2 haemagglutinin receptor-binding preference and the pH of fusion.
    Emerging Microbes & Infections 6, e11 PubMed abstract
  • Rash, A; Morton, R; Woodward, A; Maes, O; McCauley, J; Bryant, N and Elton, D (2017)
    Evolution and divergence of H3N8 equine influenza viruses circulating in the United Kingdom from 2013 to 2015.
    Pathogens 6, 6 PubMed abstract
  • Shu, Y and McCauley, J (2017)
    GISAID: Global initiative on sharing all influenza data - from vision to reality.
    Euro Surveillance 22, 30494 PubMed abstract
  • Asghar, H; Browne, HM; McCauley, J; Malik, M and Khan, W (2016)
    Contribution of laboratories in the WHO Eastern Mediterranean Region to the selection of candidate seasonal influenza vaccine, 2010-2015.
    Eastern Mediterranean Health Journal 22, 445-452 PubMed abstract
  • Benedetti, E; Daniels, RS; Pontoriero, A; Russo, M; Avaro, M; Czech, A; Campos, A; Periolo, N; Gregory, V; McCauley, JW and Baumeister, EG (2016)
    Influenza virus surveillance in Argentina during the 2012 season: antigenic characterization, genetic analysis and antiviral susceptibility.
    Epidemiology and Infection 144, 751-767 PubMed abstract
  • Harvey, WT; Benton, DJ; Gregory, V; Hall, JPJ; Daniels, RS; Bedford, T; Haydon, DT; Hay, AJ; McCauley, JW and Reeve, R (2016)
    Identification of low- and high-impact hemagglutinin amino acid substitutions that drive antigenic drift of influenza A(H1N1) viruses.
    PLOS Pathogens 12, e1005526 PubMed abstract
  • Hurt, AC; Besselaar, TG; Daniels, RS; Ermetal, B; Fry, A; Gubareva, L; Huang, W; Lackenby, A; Lee, RTC; Lo, J; Maurer-Stroh, S; Nguyen, HT; Pereyaslov, D; Rebelo-de-Andrade, H; Siqueira, MM; Takashita, E; Tashiro, M; Tilmanis, D; Wang, D; Zhang, W and Meijer, A (2016)
    Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors, 2014-2015.
    Antiviral Research 132, 178-185 PubMed abstract
  • Li, C; Hatta, M; Burke, DF; Ping, J; Zhang, Y; Ozawa, M; Taft, AS; Das, SC; Hanson, AP; Song, J; Imai, M; Wilker, PR; Watanabe, T; Watanabe, S; Ito, M; Iwatsuki-Horimoto, K; Russell, CA; James, SL; Skepner, E; Maher, EA; Neumann, G; Klimov, AI; Kelso, A; McCauley, J; Wang, D; Shu, Y; Odagiri, T; Tashiro, M; Xu, X; Wentworth, DE; Katz, JM; Cox, NJ; Smith, DJ and Kawaoka, Y (2016)
    Selection of antigenically advanced variants of seasonal influenza viruses.
    Nature Microbiology 1, 16058 PubMed abstract
  • Lin, Y; Gu, Y and McCauley, JW (2016)
    Optimization of a quantitative micro-neutralization assay.
    Journal of Visualized Experiments e54897 PubMed abstract
  • Neher, RA; Bedford, T; Daniels, RS; Russell, CA and Shraiman, BI (2016)
    Prediction, dynamics, and visualization of antigenic phenotypes of seasonal influenza viruses.
    Proceedings of the National Academy of Sciences of the United States of America 113, E1701-E1709 PubMed abstract
  • Parker, L; Wharton, SA; Martin, SR; Cross, K; Lin, Y; Liu, Y; Feizi, T; Daniels, RS and McCauley, JW (2016)
    Effects of egg-adaptation on receptor-binding and antigenic properties of recent Influenza A (H3N2) vaccine viruses.
    Journal of General Virology 97, 1333-1344 PubMed abstract
  • Ruiz-Hernandez, R; Mwangi, W; Peroval, M; Sadeyen, J-R; Ascough, S; Balkissoon, D; Staines, K; Boyd, A; McCauley, J; Smith, A and Butter, C (2016)
    Host genetics determine susceptibility to avian influenza infection and transmission dynamics.
    Scientific Reports 6, 26787 PubMed abstract
  • Suphaphiphat, P; Whittaker, L; De Souza, I; Daniels, RS; Dormitzer, PR; McCauley, JW and Settembre, EC (2016)
    Antigenic characterization of influenza viruses produced using synthetic DNA and novel backbones.
    Vaccine 34, 3641-3648 PubMed abstract
  • Turnbull, ML; Wise, HM; Nicol, MQ; Smith, N; Dunfee, RL; Beard, PM; Jagger, BW; Ligertwood, Y; Hardisty, GR; Xiao, H; Benton, DJ; Coburn, AM; Paulo, JA; Gygi, SP; McCauley, JW; Taubenberger, JK; Lycett, SJ; Weekes, MP; Dutia, BM and Digard, P (2016)
    The role of the B-allele of the influenza A virus segment 8 in setting mammalian host range and pathogenicity.
    Journal of Virology 90, 9263-9284 PubMed abstract
  • Bedford, T; Riley, S; Barr, IG; Broor, S; Chadha, M; Cox, NJ; Daniels, RS; Gunasekaran, CP; Hurt, AC; Kelso, A; Klimov, A; Lewis, NS; Li, X; McCauley, JW; Odagiri, T; Potdar, V; Rambaut, A; Shu, Y; Skepner, E; Smith, DJ; Suchard, MA; Tashiro, M; Wang, D; Xu, X; Lemey, P and Russell, CA (2015)
    Global circulation patterns of seasonal influenza viruses vary with antigenic drift.
    Nature 523, 217-220 PubMed abstract
  • Benton, DJ; Martin, SR; Wharton, SA and McCauley, JW (2015)
    Biophysical measurement of the balance of influenza A hemagglutinin and neuraminidase activities.
    Journal of Biological Chemistry 290, 6516-6521 PubMed abstract
  • Brown, JR; Tang, JW; Pankhurst, L; Klein, N; Gant, V; Lai, KM; McCauley, J and Breuer, J (2015)
    Influenza virus survival in aerosols and estimates of viable virus loss resulting from aerosolization and air-sampling.
    Journal of Hospital Infection 91, 278-281 PubMed abstract
  • Goddard, N; Rebelo-de-Andrade, H; Meijer, A; McCauley, J; Daniels, R and Zambon, M (2015)
    Future directions for the European influenza reference laboratory network in influenza surveillance.
    Euro Surveillance 20, 21195 PubMed abstract
  • Huang, K-YA; Rijal, P; Schimanski, L; Powell, TJ; Lin, T-Y; McCauley, JW; Daniels, RS and Townsend, AR (2015)
    Focused antibody response to influenza linked to antigenic drift.
    Journal of Clinical Investigation 125, 2631-2645 PubMed abstract
  • Hurt, AC; Hui, DS; Hay, A and Hayden, FG (2015)
    Overview of the 3rd isirv-Antiviral Group conference - advances in clinical management.
    Influenza and Other Respiratory Viruses 9, 20-31 PubMed abstract
  • Hussain, S; Miller, JL; Harvey, DJ; Gu, Y; Rosenthal, PB; Zitzmann, N and McCauley, JW (2015)
    Strain-specific antiviral activity of iminosugars against human influenza A viruses.
    Journal of Antimicrobial Chemotherapy 70, 136-152 PubMed abstract
  • Lin, Y; Gu, Y; Wharton, SA; Whittaker, L; Gregory, V; Li, X; Metin, S; Cattle, N; Daniels, RS; Hay, AJ and McCauley, JW (2015)
    Optimisation of a micro-neutralisation assay and its application in antigenic characterisation of influenza viruses.
    Influenza and Other Respiratory Viruses 9, 331-340 PubMed abstract
  • Pereyaslov, D; Zemtsova, G; Gruessner, C; Daniels, RS; McCauley, JW and Brown, CS (2015)
    Improving the representativeness of influenza viruses shared within the WHO global influenza surveillance and response system.
    Influenza and Other Respiratory Viruses 10, 68-75 PubMed abstract
  • Xiong, X; Corti, D; Liu, J; Pinna, D; Foglierini, M; Calder, LJ; Martin, SR; Lin, YP; Walker, PA; Collins, PJ; Monne, I; Suguitan, AL, Jr.; Santos, C; Temperton, NJ; Subbarao, K; Lanzavecchia, A; Gamblin, SJ and Skehel, JJ (2015)
    Structures of complexes formed by H5 influenza hemagglutinin with a potent broadly neutralizing human monoclonal antibody.
    Proceedings of the National Academy of Sciences of the United States of America 112, 9430-9435 PubMed abstract
  • Barr, IG; Russell, C; Besselaar, TG; Cox, NJ; Daniels, RS; Donis, R; Engelhardt, OG; Grohmann, G; Itamura, S; Kelso, A; McCauley, J; Odagiri, T; Schultz-Cherry, S; Shu, Y; Smith, D; Tashiro, M; Wang, D; Webby, R; Xu, X; Ye, Z and Zhang, W (2014)
    WHO recommendations for the viruses used in the 2013-2014 Northern Hemisphere influenza vaccine: Epidemiology, antigenic and genetic characteristics of influenza A(H1N1)pdm09, A(H3N2) and B influenza viruses collected from October 2012 to January 2013.
    Vaccine 32, 4713-4725 PubMed abstract
  • Bedford, T; Suchard, MA; Lemey, P; Dudas, G; Gregory, V; Hay, AJ; McCauley, JW; Russell, CA; Smith, DJ and Rambaut, A (2014)
    Integrating influenza antigenic dynamics with molecular evolution.
    eLife 3, e01914 PubMed abstract
  • Bradley-Stewart, A; Miller, RS; MacLean, A; Aitken, C; Whittaker, L; Gregory, V; Daniels, R and Gunson, R (2014)
    Cluster of influenza A cases in vaccinated population of adults in Virology Laboratory in Glasgow in December 2012.
    Scottish Medical Journal 59, 95-102 PubMed abstract
  • Broberg, E; Pereyaslov, D; Struelens, M; Palm, D; Meijer, A; Ellis, J; Zambon, M; McCauley, J and Daniels, R (2014)
    Laboratory preparedness in EU/EEA countries for detection of novel avian influenza A(H7N9) virus, May 2013.
    Euro Surveillance 19, 20682 PubMed abstract
  • Escuret, V; Collins, PJ; Casalegno, J-S; Vachieri, SG; Cattle, N; Ferraris, O; Sabatier, M; Frobert, E; Caro, V; Skehel, JJ; Gamblin, S; Valla, F; Valette, M; Ottmann, M; McCauley, JW; Daniels, RS and Lina, B (2014)
    A novel I221L substitution in neuraminidase confers high-level resistance to oseltamivir in influenza B viruses.
    Journal of Infectious Diseases 210, 1260-1269 PubMed abstract
  • Gonzalez, G; Marshall, JF; Morrell, J; Robb, D; McCauley, JW; Perez, DR; Parrish, CR and Murcia, PR (2014)
    Infection and pathogenesis of canine, equine and human influenza viruses in canine tracheas.
    Journal of Virology 88, 9208-9219 PubMed abstract
  • Iqbal, M; Reddy, KB; Brookes, SM; Essen, SC; Brown, IH and McCauley, JW (2014)
    Virus pathotype and deep sequencing of the HA gene of a low pathogenicity H7N1 avian influenza virus causing mortality in turkeys.
    PLOS ONE 9, e87076 PubMed abstract
  • Le, TT; Adamiak, B; Benton, DJ; Johnson, CJ; Sharma, S; Fenton, R; McCauley, JW; Iqbal, M and Cass, AEG (2014)
    Aptamer-based biosensors for the rapid visual detection of flu viruses.
    Chemical Communications 50, 15533-15536 PubMed abstract
  • Meijer, A; Rebelo-de-Andrade, H; Correia, V; Besselaar, T; Dayal, RD; Fry, A; Gregory, V; Gubareva, L; Kageyama, T; Lackenby, A; Lo, J; Odagiri, T; Pereyaslov, D; Siqueira, MM; Takashita, E; Tashiro, M; Wang, D; Wong, S; Zhang, W; Daniels, RS and Hurt, AC (2014)
    Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors, 2012-2013.
    Antiviral Research 110, 31-41 PubMed abstract
  • Puzelli, S; Rossini, G; Facchini, M; Vaccari, G; Di Trani, L; Di Martino, A; Gaibani, P; Vocale, C; Cattoli, G; Bennett, M; McCauley, JW; Rezza, G; Moro, ML; Rangoni, R; Finarelli, AC; Landini, MP; Castrucci, MR; Donatelli, I and Influenza Task Force (2014)
    Human infection with highly pathogenic A(H7N7) avian influenza virus, Italy, 2013.
    Emerging Infectious Diseases 20, 1745-1749 PubMed abstract
  • Rash, A; Woodward, A; Bryant, N; McCauley, J and Elton, D (2014)
    An efficient genome sequencing method for equine influenza [H3N8] virus reveals a new polymorphism in the PA-X protein.
    Virology Journal 11, 159 PubMed abstract
  • Schultz-Cherry, S; Webby, RJ; Webster, RG; Kelso, A; Barr, IG; McCauley, JW; Daniels, RS; Wang, D; Shu, Y; Nobusawa, E; Itamura, S; Tashiro, M; Harada, Y; Watanabe, S; Odagiri, T; Ye, Z; Grohmann, G; Harvey, R; Engelhardt, O; Smith, D; Hamilton, K; Claes, F and Dauphin, G (2014)
    Influenza gain-of-function experiments: their role in vaccine virus recommendation and pandemic preparedness.
    mBio 5, e02430-02414 PubMed abstract
  • Sherbany, H; McCauley, J; Meningher, T; Hindiyeh, M; Dichtiar, R; Mandelboim, M and Mendelson, E (2014)
    Return of pandemic H1N1 influenza virus.
    BMC Infectious Diseases 14, 3848 PubMed abstract
  • Streicher, H; Martin, SR; Coombs, PJ; McCauley, J; Neill-Hall, D and Stanley, M (2014)
    A phospha-oseltamivir-biotin conjugate as a strong and selective adhesive for the influenza virus.
    Bioorganic & Medicinal Chemistry Letters 24, 1805-1807 PubMed abstract
  • Trebbien, R; Andersen, B; Rønn, J; McCauley, J and Kølsen Fischer, T (2014)
    ESwab challenges influenza virus propagation in cell cultures.
    Euro Surveillance 19, pii: 20995 PubMed abstract
  • Vachieri, SG; Xiong, X; Collins, PJ; Walker, PA; Martin, SR; Haire, LF; Zhang, Y; McCauley, JW; Gamblin, SJ and Skehel, JJ (2014)
    Receptor binding by H10 influenza viruses.
    Nature 511, 475-477 PubMed abstract
  • Woodward, AL; Rash, AS; Blinman, D; Bowman, S; Chambers, TM; Daly, JM; Damiani, A; Joseph, S; Lewis, N; McCauley, JW; Medcalf, L; Mumford, J; Newton, JR; Tiwari, A; Bryant, NA and Elton, DM (2014)
    Development of a surveillance scheme for equine influenza in the UK and characterisation of viruses isolated in Europe, Dubai and the USA from 2010-2012.
    Veterinary Microbiology 169, 113-127 PubMed abstract
  • World Health Organization (2014)
    Recommended composition of influenza virus vaccines for use in the 2014-2015 northern hemisphere influenza season.
    Weekly Epidemiological Record 89, 93-104 PubMed abstract
  • Xiong, X; McCauley, JW and Steinhauer, DA (2014)
    Receptor binding properties of the influenza virus hemagglutinin as a determinant of host range.
    Current Topics in Microbiology and Immunology 385, 63-91 PubMed abstract
  • Xiong, X; Xiao, H; Martin, SR; Coombs, PJ; Liu, J; Collins, PJ; Vachieri, SG; Walker, PA; Lin, YP; McCauley, JW; Gamblin, SJ and Skehel, JJ (2014)
    Enhanced human receptor binding by H5 haemagglutinins.
    Virology 456-457, 179-187 PubMed abstract
  • Zhang, X-S; Pebody, R; De Angelis, D; White, PJ; Charlett, A and McCauley, JW (2014)
    The possible impact of vaccination for seasonal influenza on emergence of pandemic influenza via reassortment.
    PLOS ONE 9, e114637 PubMed abstract
  • Al Busaidy, S; Al-Gohary, A; Ampofo, WK; Bekshin, Z; Cerkaoui, I; Claes, F; Cox, NJ; Cracknell, W; Cui, L; de Paiva, TM; de Wit, M; Diep, LDT; Donabedian, A; Donis, R; Dormitzer, PR; Eichelberger, M; El Kholy, N; Engelhardt, O; Engelmann, HB; Eropkin, MY; Fasce, R; Fontaine, L; Ghadakchi, HF; Ghedin, E; Giovanni, MY; Golding, H; Gomes da Silva, HC; Gysin, R; Hamilton, K; Hauge, SH; Hay, A; Huang, S; Hungnes, O; Ibrahim, SSS; Immamura, T; Inglis, SC; Kadjo, H; Katz, J; Kawaoka, Y; Kelso, A; Khan, MI; Kilander, A; Klimov, A; Kreij, K; Kusmiaty, D; Linde, A; Liu, M-T; Lupulescu, E; Mai, LQ; Martínez, VR; McCauley, J; Meyer, Q; Modi, R; Mohammadi, AA; Mokhtari-Azad, T; Mol, E; Music, T; Nelson, K; Neuhaus, E; Neumeier, ER; Niang, MN; Odagiri, T; Peiris, M; Pohlmann, A; Popow-Kraupp, T; Trilar, KP; Rabadan, R; Rambaut, A; Robertson, JS; Rolls, C; Sampurno, OD; Savy, V; Sawanpanyaltert, P; Schmid, G; Schweiger, B; Shapira, S; Shinde, V; Shu, Y; Siqueira, M; Smith, D; Spiro, D; Stevens, J; Takizawa, K; Tashiro, M; Taylor, B; Thomas, Y; Tsai, T; Van der Werf, S; Venter, M; Waddell, AL; Wan, X; Wang, D; Webby, R; Weir, JP; Wentworth, D; Wickramasinghe, G; Ye, Z; Zambon, M and Ziegler, T (2013)
    Strengthening the influenza vaccine virus selection and development process: Outcome of the 2nd WHO Informal Consultation for Improving Influenza Vaccine Virus Selection held at the Centre International de Conférences (CICG) Geneva, Switzerland, 7 to 9 December 2011.
    Vaccine 31, 3209-3221 PubMed abstract
  • Ampofo, WK; Baylor, N; Cobey, S; Cox, NJ; Daves, S; Edwards, S; Ferguson, N; Grohmann, G; Hay, A; Katz, J; Kullabutr, K; Lambert, L; Levandowski, R; Mishra, AC; Monto, A; Siqueira, M; Tashiro, M; Waddell, AL; Wairagkar, N; Wood, J; Zambon, M and Zhang, WQ (2013)
    Improving influenza vaccine virus selection: report of a WHO informal consultation held at WHO headquarters, Geneva, Switzerland, 14-16 June 2010.
    Influenza and Other Respiratory Viruses 7, 52-53 PubMed abstract
  • Fordyce, S; Bragstad, K; Pedersen, SS; Jensen, T; Gahrn-Hansen, B; Daniels, R; Hay, A; Kampmann, M-L; Bruhn, C; Moreno-Mayar, JV; Avila-Arcos, M; Gilbert, MT and Nielsen, L (2013)
    Genetic diversity among pandemic 2009 influenza viruses isolated from a transmission chain.
    Virology Journal 10, 116 PubMed abstract
  • Hay, AJ and Hayden, FG (2013)
    Oseltamivir resistance during treatment of H7N9 infection.
    Lancet 381, 2230-2232 PubMed abstract
  • Hurt, AC; Ison, MG; Hayden, FG and Hay, AJ (2013)
    Second isirv antiviral group conference: overview.
    Influenza and Other Respiratory Viruses 7 , 1-7 PubMed abstract
  • Iqbal, M; Yaqub, T; Mukhtar, N; Shabbir, MZ and McCauley, JW (2013)
    Infectivity and transmissibility of H9N2 avian influenza virus in chickens and wild terrestrial birds.
    Veterinary Research 44, 100 PubMed abstract
  • Marín, MJ; Rashid, A; Rejzek, M; Fairhurst, SA; Wharton, SA; Martin, SR; McCauley, JW; Wileman, T; Field, RA and Russell, DA (2013)
    Glyconanoparticles for the plasmonic detection and discrimination between human and avian influenza virus.
    Organic & Biomolecular Chemistry 11, 7101-7107 PubMed abstract
  • Pozo, F; Lina, B; Andrade, HRd; Enouf, V; Kossyvakis, A; Broberg, E; Daniels, R; Lackenby, A and Meijer, A (2013)
    Guidance for clinical and public health laboratories testing for influenza virus antiviral drug susceptibility in Europe.
    Journal of Clinical Virology 57, 5-12 PubMed abstract
  • Reis, AL and McCauley, JW (2013)
    The influenza virus protein PB1-F2 interacts with IKKβ and modulates NF-κB signalling.
    PLOS ONE 8, e63852 PubMed abstract
  • World Health Organization (2013)
    Recommended composition of influenza virus vaccines for use in the 2013-2014 northern hemisphere influenza season.
    Weekly Epidemiological Record 88, 101-114 PubMed abstract
  • Xiong, X; Coombs, PJ; Martin, SR; Liu, J; Xiao, H; McCauley, JW; Locher, K; Walker, PA; Collins, PJ; Kawaoka, Y; Skehel, JJ and Gamblin, SJ (2013)
    Receptor binding by a ferret-transmissible H5 avian influenza virus.
    Nature 497, 392-396 PubMed abstract
  • Xiong, X; Martin, SR; Haire, LF; Wharton, SA; Daniels, RS; Bennett, MS; McCauley, JW; Collins, PJ; Walker, PA; Skehel, JJ and Gamblin, SJ (2013)
    Receptor binding by an H7N9 influenza virus from humans.
    Nature 499, 496-499 PubMed abstract
  • Zhang, X-S; De Angelis, D; White, PJ; Charlett, A; Pebody, RG and McCauley, J (2013)
    Co-circulation of influenza A virus strains and emergence of pandemic via reassortment: the role of cross-immunity.
    Epidemics 5, 20-33 PubMed abstract
  • Ampofo, WK; Baylor, N; Cobey, S; Cox, NJ; Daves, S; Edwards, S; Ferguson, N; Grohmann, G; Hay, A; Katz, J; Kullabutr, K; Lambert, L; Levandowski, R; Mishra, AC; Monto, A; Siqueira, M; Tashiro, M; Waddell, AL; Wairagkar, N; Wood, J; Zambon, M and Zhang, W (2012)
    Improving influenza vaccine virus selection. Report of a WHO informal consultation held at WHO headquarters, Geneva, Switzerland, 14-16 June 2010.
    Influenza and Other Respiratory Viruses 6, 14-152 PubMed abstract
  • Galiano, M; Johnson, BF; Myers, R; Ellis, J; Daniels, R and Zambon, M (2012)
    Fatal cases of influenza A(H3N2) in children: insights from whole genome sequence analysis.
    PLOS ONE 7, e33166 PubMed abstract
  • Hurt, AC; Chotpitayasunondh, T; Cox, NJ; Daniels, R; Fry, AM; Gubareva, LV; Hayden, FG; Hui, DS; Hungnes, O; Lackenby, A; Lim, W; Meijer, A; Penn, C; Tashiro, M; Uyeki, TM and Zambon, M (2012)
    Antiviral resistance during the 2009 influenza A H1N1 pandemic: public health, laboratory, and clinical perspectives.
    Lancet Infectious Diseases 12, 240-248
  • Iqbal, M; Essen, SC; Xiao, H; Brookes, SM; Brown, IH and McCauley, JW (2012)
    Selection of variant viruses during replication and transmission of H7N1 viruses in chickens and turkeys.
    Virology 433, 282-295 PubMed abstract
  • Klimov, AI; Garten, R; Russell, C; Barr, IG; Besselaar, TG; Daniels, R; Engelhardt, OG; Grohmann, G; Itamura, S; Kelso, A; McCauley, J; Odagiri, T; Smith, D; Tashiro, M; Xu, X; Webby, R; Wang, D; Ye, Z; Yuelong, S; Zhang, W and Cox, N (2012)
    WHO recommendations for the viruses to be used in the 2012 Southern Hemisphere Influenza Vaccine: epidemiology, antigenic and genetic characteristics of influenza A(H1N1)pdm09, A(H3N2) and B influenza viruses collected from February to September 2011.
    Vaccine 30, 6461-6471 PubMed abstract
  • Lin, YP; Xiong, X; Wharton, SA; Martin, SR; Coombs, PJ; Vachieri, SG; Christodoulou, E; Walker, PA; Liu, J; Skehel, JJ; Gamblin, SJ; Hay, AJ; Daniels, RS and McCauley, JW (2012)
    Evolution of the receptor binding properties of the influenza A(H3N2) hemagglutinin.
    Proceedings of the National Academy of Sciences of the United States of America 109, 21474-21479 PubMed abstract
  • Lycett, SJ; Baillie, G; Coulter, E; Bhatt, S; Kellam, P; McCauley, JW; Wood, JLN; Brown, IH; Pybus, OG; Leigh Brown, AJ and Combating Swine Influenza Initiative (COSI) Consortium (2012)
    Estimating reassortment rates in co-circulating Eurasian swine influenza viruses.
    Journal of General Virology 93, 2326-2336 PubMed abstract
  • Niang, MN; Dosseh, A; Ndiaye, K; Sagna, M; Gregory, V; Goudiaby, D; Hay, A and Diop, OM (2012)
    Sentinel surveillance for influenza in Senegal, 1996-2009.
    Journal of Infectious Diseases 206, S129-S135 PubMed abstract
  • Saenz, RA; Essen, SC; Brookes, SM; Iqbal, M; Wood, JLN; Grenfell, BT; McCauley, JW; Brown, IH and Gog, JR (2012)
    Quantifying transmission of highly pathogenic and low pathogenicity H7N1 avian influenza in turkeys.
    PLOS ONE 7, e45059 PubMed abstract
  • Sullivan, K; Kloess, J; Qian, C; Bell, D; Hay, A; Lin, YP and Gu, Y (2012)
    High throughput virus plaque quantitation using a flatbed scanner.
    Journal of Virological Methods 179, 81-89 PubMed abstract
  • Thompson, CI; Lackenby, A; Daniels, RS; McCauley, JW; Pereyaslov, D; Broberg, EK; Meijer, A and Zambon, MC (2012)
    Evaluation of influenza virus antiviral susceptibility testing in Europe: Results from the first external quality assessment exercise.
    Journal of Clinical Virology 56, 212-218 PubMed abstract
  • van der Vries, E; Collins, PJ; Vachieri, SG; Xiong, X; Liu, J; Walker, PA; Haire, LF; Hay, AJ; Schutten, M; Osterhaus, ADME; Martin, SR; Boucher, CAB; Skehel, JJ and Gamblin, SJ (2012)
    H1N1 2009 pandemic influenza virus: resistance of the I223R neuraminidase mutant explained by kinetic and structural analysis.
    PLOS Pathogens 8, e1002914 PubMed abstract
  • Büch, J; Roomp, K; Bach, G; Steinbrück, L; Beer, M; Gregory, V; Komadina, N; Lan, Y; Monne, I; Smith, C; Fujisaki, S; Bogner, P and Lengauer, T (2011)
    GISAID - a global initiative on sharing all influenza data.
    Influenza and Other Respiratory Viruses 5, 419-419
  • dos Reis, M; Tamuri, AU; Hay, AJ and Goldstein, RA (2011)
    Charting the host adaptation of influenza viruses.
    Molecular Biology and Evolution 28, 1755-1767 PubMed abstract
  • Moules, V; Terrier, O; Yver, M; Riteau, B; Moriscot, C; Ferraris, O; Julien, T; Giudice, E; Rolland, JP; Erny, A; Bouscambert-Duchamp, M; Frobert, E; Rosa-Calatrava, M; Lin, YP; Hay, A; Thomas, D; Schoehn, G and Lina, B (2011)
    Importance of viral genomic composition in modulating glycoprotein content on the surface of influenza virus particles.
    Virology 414, 51-62 PubMed abstract
  • Skehel, JJ (2011)
    Research in a pandemic context.
    Influenza and Other Respiratory Viruses 5, 37-40
  • Ampofo, WK; Kronmann, KC; Adjabeng, M; Bonney, K; Asante, IA; Nzussouo, NT; Davies, R; Addo-Yobo, F; Parbie, P; Opata, H; McCauley, J; Pimentel, G; Barthel, RV; Oyofo, BA; Ahadzie, L and Amankwa, J (2010)
    Hospital-based surveillance for influenza viruses in Ghana, West Africa.
    American Journal of Tropical Medicine and Hygiene 83, 264 Abstract No.883
  • Barr, IG; McCauley, J; Cox, N; Daniels, R; Engelhardt, OG; Fukuda, K; Grohmann, G; Hay, A; Kelso, A; Klimov, A; Odagiri, T; Smith, D; Russell, C; Tashiro, M; Webby, R; Wood, J; Ye, Z and Zhang, W (2010)
    Epidemiological, antigenic and genetic characteristics of seasonal influenza A(H1N1), A(H3N2) and B influenza viruses: basis for the WHO recommendation on the composition of influenza vaccines for use in the 2009-2010 Northern Hemisphere season.
    Vaccine 28, 1156-1167 PubMed abstract
  • Chen, Z; Zheng, YH; Lin, Y; Collins, PJ and Hay, AJ (2010)
    [Impact of avian influenza virus H5N1 neuraminidase mutations on the activity of neuraminidase and the sensibility to neuraminidase inhibitors.].
    Zhonghua Yi Xue Za Zhi 90, 1924-1928 PubMed abstract
  • Gamlen, T; Richards, K; Mankouri, J; Hudson, L; McCauley, J; Harris, M and Macdonald, A (2010)
    Expression of the NS3 protease of cytopathogenic BVDV results in the induction of apoptosis but does not block activation of the interferon-β promoter.
    Journal of General Virology 91, 133-144 PubMed abstract
  • Hay, A (2010)
    WHO process for monitoring novel influenza viruses.
    Influenza and Other Respiratory Viruses 4, 36 Abstract 32.34
  • Krashias, G; Simon, A-K; Wegmann, F; Kok, W-L; Ho, L-P; Stevens, D; Skehel, J; Heeney, JL; Moghaddam, AE and Sattentau, QJ (2010)
    Potent adaptive immune responses induced against HIV-1 gp140 and influenza virus HA by a polyanionic carbomer.
    Vaccine 28, 2482-2489 PubMed abstract
  • Lin, YP; Gregory, V; Collins, P; Kloess, J; Wharton, S; Cattle, N; Lackenby, A; Daniels, R and Hay, A (2010)
    Neuraminidase receptor binding variants of human influenza A(H3N2) viruses due to substitution of aspartic acid 151 in the catalytic site - role in virus attachment?
    Journal of Virology 84, 6769-6781 PubMed abstract
  • Liu, Y; Childs, RA; Matrosovich, T; Wharton, S; Palma, AS; Chai, W; Daniels, R; Gregory, V; Uhlendorff, J; Kiso, M; Klenk, H-D; Hay, A; Feizi, T and Matrosovich, M (2010)
    Altered receptor specificity and cell tropism of D222G haemagglutinin mutants from fatal cases of pandemic A(H1N1) 2009 influenza.
    Journal of Virology 84, 12069-12074 PubMed abstract
  • Moules, V; Ferraris, O; Terrier, O; Giudice, E; Yver, M; Rolland, JP; Bouscambert-Duchamp, M; Bergeron, C; Ottmann, M; Fournier, E; Traversier, A; Boule, C; Rivoire, A; Lin, Y; Hay, A; Valette, M; Marquet, R; Rosa-Calatrava, M; Naffakh, N; Schoehn, G; Thomas, D and Lina, B (2010)
    In vitro characterization of naturally occurring influenza H3NA- viruses lacking the NA gene segment: Toward a new mechanism of viral resistance?
    Virology 404, 215-224 PubMed abstract
  • Murcia, PR; Baillie, GJ; Daly, J; Elton, D; Jervis, C; Mumford, JA; Newton, R; Parrish, CR; Hoelzer, K; Dougan, G; Parkhill, J; Lennard, N; Ormond, D; Moule, S; Whitwham, A; McCauley, JW; McKinley, TJ; Holmes, EC; Grenfell, BT and Wood, JLN (2010)
    The intra- and inter-host evolutionary dynamics of equine influenza virus.
    Journal of Virology 84, 6943-6954 PubMed abstract
  • Njouom, R; Mba, SAS; Noah, DN; Gregory, V; Collins, P; Cappy, P; Hay, A and Rousset, D (2010)
    Circulation of human influenza viruses and emergence of Oseltamivir-resistant A(H1N1) viruses in Cameroon, Central Africa.
    BMC Infectious Diseases 10, 56 PubMed abstract
  • Saenz, RA; Quinlivan, M; Elton, D; MacRae, S; Blunden, AS; Mumford, JA; Daly, JM; Digard, P; Cullinane, A; Grenfell, BT; McCauley, JW; Wood, JLN and Gog, JR (2010)
    Dynamics of infection and pathology in influenza.
    Journal of Virology 84, 3974-3983 PubMed abstract
  • Thébaud, G; Chadœuf, J; Morelli, MJ; McCauley, JW and Haydon, DT (2010)
    The relationship between mutation frequency and replication strategy in positive-sense single-stranded RNA viruses.
    Proceedings of the Royal Society B: Biological Sciences 277, 809-817 PubMed abstract
  • Yavarian, J; Azad, TM; Zheng, X; Gregory, V; Lin, YP and Hay, A (2010)
    Amantadine resistance in relation to the evolution of influenza A(H3N2) viruses in Iran.
    Antiviral Research 88, 193-196 PubMed abstract

[Page last updated 1 Jul 2018]


Tel: +44 (0)203 796 0563

Dr John McCauley
(Director of WIC)
Tel: +44 (0)203 796 1520

Dr Rod Daniels
(Deputy Director)
Tel: +44 (0)203 796 2444

Dr Yi Pu Lin 
(Assistant Director)
Tel: +44 (0)203 796 1508