Research case studies Explore a selection of reports that spotlight particular areas of research at the Crick over the past five years.
Postdoctoral clinical fellows Opportunities for postdoctoral clinicians to consolidate their research experience.
Search Results Fulltext search 13385 Results Found On the pivotal role of PPARα in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury Authors (20) Mark A Cole Amira H Abd Jamil Lisa C Heather Andrew J Murray Elizabeth R Sutton Mary Slingo[...] Christopher J SchofieldPeter Ratcliffe Stefan Neubauer Peter A Robbins Kieran Clarke FASEB Journal Published 1 August 2016 Crick labsPeter RatcliffeFull details Epibranchial ganglia orchestrate the development of the cranial neurogenic crest Authors (8) Eva Coppola Murielle Rallu Juliette Richard Sylvie Dufour Dieter RiethmacherFrancois Guillemot Christo Goridis Jean-François Brunet Proceedings of the National Academy of Sciences of the United States of America Published 2 February 2010 Crick labsFrancois GuillemotFull details Guidelines for the use of flow cytometry and cell sorting in immunological studies Authors (231) Andrea Cossarizza Hyun-Dong Chang Andreas Radbruch Immanuel Andrä Francesco Annunziato Petra Bacher[...] Alice Yue Qianjun Zhang Yi Zhao Susanne Ziegler Jakob Zimmermann European Journal of Immunology Published 1 October 2017 Crick labs/ facilitiesFlow CytometryFull details microRNA-9 regulates axon extension and branching by targeting Map1b in mouse cortical neurons Authors (6) F Dajas-Bailador B Bonev P Garcez P StanleyFrancois Guillemot N Papalopulu Nature Neuroscience Published 1 January 2012 Crick labsFrancois GuillemotFull details Design, synthesis and characterization of N-oxide-containing heterocycles with in vivo sterilizing antitubercular activity Authors (26) Guilherme Felipe dos Santos Fernandes Paula Carolina de Souza Elsa Moreno-Viguri Mery Santivañez-Veliz Rocio Paucar Silvia Pérez-Silanes[...] Sang Hyun Cho Yuehong Wang Scott Gary Franzblau Fernando Rogério Pavan Jean Leandro dos Santos Journal of Medicinal Chemistry Published 2 October 2017 Crick labsLuiz Pedro CarvalhoFull details Deconvoluting AMP-activated protein kinase (AMPK) adenine nucleotide binding and sensing Authors (14) Xin Gu Yan Yan Scott J Novick Amanda Kovach Devrishi Goswami Jiyuan Ke[...] Parker W de Waal Martin R Webb Patrick R Griffin H Eric Xu Karsten Melcher Journal of Biological Chemistry Published 28 July 2017Full details From cradle to grave: the multiple roles of fibroblast growth factors in neural development Authors (2)Francois Guillemot C Zimmer Neuron Published 25 August 2011 Crick labsFrancois GuillemotFull details Parasitophorous vacuole poration precedes its rupture and rapid host erythrocyte cytoskeleton collapse in Plasmodium falciparum egress Authors (12) Victoria L Hale Jean M Watermeyer Fiona Hackett Gema Vizcay-Barrena Christiaan Van Ooij James A Thomas[...] Maria Harkiolaki Elizabeth Duke Roland A FleckMichael Blackman Helen R Saibil Proceedings of the National Academy of Sciences of the United States of America Published 28 March 2017 Crick labsMike BlackmanFull details NFIX regulates proliferation and migration within the murine SVZ neurogenic niche Authors (16) Yee Hsieh Evelyn Heng Bo ZhouLachlan Harris Tracey Harvey Aaron Smith Elise Horne[...] Richard M Gronostajski Giles S YeoFrancois Guillemot Timothy L Bailey Michael Piper Cerebral Cortex Published 1 October 2015 Crick labsFrancois GuillemotFull details Reactivation of p53 by a cytoskeletal sensor to control the balance between DNA damage and tumor dissemination Authors (10) Cecilia Herraiz Fernando Calvo Pahini Pandya Gaia Cantelli Irene Rodriguez-Hernandez Jose L Orgaz NaRa Kang Tinghine ChuErik Sahai Victoria Sanz-Moreno Journal of the National Cancer Institute Published 1 January 2016 Crick labsErik SahaiFull details Pagination First page First Previous page Previous … Page 870 Page 871 Page 872 Page 873 Current page 874 Page 875 Page 876 Page 877 Page 878 … Next page Next Last page Last
On the pivotal role of PPARα in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury Authors (20) Mark A Cole Amira H Abd Jamil Lisa C Heather Andrew J Murray Elizabeth R Sutton Mary Slingo[...] Christopher J SchofieldPeter Ratcliffe Stefan Neubauer Peter A Robbins Kieran Clarke FASEB Journal Published 1 August 2016 Crick labsPeter RatcliffeFull details
Epibranchial ganglia orchestrate the development of the cranial neurogenic crest Authors (8) Eva Coppola Murielle Rallu Juliette Richard Sylvie Dufour Dieter RiethmacherFrancois Guillemot Christo Goridis Jean-François Brunet Proceedings of the National Academy of Sciences of the United States of America Published 2 February 2010 Crick labsFrancois GuillemotFull details
Guidelines for the use of flow cytometry and cell sorting in immunological studies Authors (231) Andrea Cossarizza Hyun-Dong Chang Andreas Radbruch Immanuel Andrä Francesco Annunziato Petra Bacher[...] Alice Yue Qianjun Zhang Yi Zhao Susanne Ziegler Jakob Zimmermann European Journal of Immunology Published 1 October 2017 Crick labs/ facilitiesFlow CytometryFull details
microRNA-9 regulates axon extension and branching by targeting Map1b in mouse cortical neurons Authors (6) F Dajas-Bailador B Bonev P Garcez P StanleyFrancois Guillemot N Papalopulu Nature Neuroscience Published 1 January 2012 Crick labsFrancois GuillemotFull details
Design, synthesis and characterization of N-oxide-containing heterocycles with in vivo sterilizing antitubercular activity Authors (26) Guilherme Felipe dos Santos Fernandes Paula Carolina de Souza Elsa Moreno-Viguri Mery Santivañez-Veliz Rocio Paucar Silvia Pérez-Silanes[...] Sang Hyun Cho Yuehong Wang Scott Gary Franzblau Fernando Rogério Pavan Jean Leandro dos Santos Journal of Medicinal Chemistry Published 2 October 2017 Crick labsLuiz Pedro CarvalhoFull details
Deconvoluting AMP-activated protein kinase (AMPK) adenine nucleotide binding and sensing Authors (14) Xin Gu Yan Yan Scott J Novick Amanda Kovach Devrishi Goswami Jiyuan Ke[...] Parker W de Waal Martin R Webb Patrick R Griffin H Eric Xu Karsten Melcher Journal of Biological Chemistry Published 28 July 2017Full details
From cradle to grave: the multiple roles of fibroblast growth factors in neural development Authors (2)Francois Guillemot C Zimmer Neuron Published 25 August 2011 Crick labsFrancois GuillemotFull details
Parasitophorous vacuole poration precedes its rupture and rapid host erythrocyte cytoskeleton collapse in Plasmodium falciparum egress Authors (12) Victoria L Hale Jean M Watermeyer Fiona Hackett Gema Vizcay-Barrena Christiaan Van Ooij James A Thomas[...] Maria Harkiolaki Elizabeth Duke Roland A FleckMichael Blackman Helen R Saibil Proceedings of the National Academy of Sciences of the United States of America Published 28 March 2017 Crick labsMike BlackmanFull details
NFIX regulates proliferation and migration within the murine SVZ neurogenic niche Authors (16) Yee Hsieh Evelyn Heng Bo ZhouLachlan Harris Tracey Harvey Aaron Smith Elise Horne[...] Richard M Gronostajski Giles S YeoFrancois Guillemot Timothy L Bailey Michael Piper Cerebral Cortex Published 1 October 2015 Crick labsFrancois GuillemotFull details
Reactivation of p53 by a cytoskeletal sensor to control the balance between DNA damage and tumor dissemination Authors (10) Cecilia Herraiz Fernando Calvo Pahini Pandya Gaia Cantelli Irene Rodriguez-Hernandez Jose L Orgaz NaRa Kang Tinghine ChuErik Sahai Victoria Sanz-Moreno Journal of the National Cancer Institute Published 1 January 2016 Crick labsErik SahaiFull details