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The Francis Crick Institute has repurposed its laboratory facilities to become a COVID-19 testing facility, to help combat the spread of infection and allow key workers to perform lifesaving duties and remain safe.

The COVID-19 outbreak requires a concerted research effort - at the Crick researchers are looking at how the virus interacts with our body and how the virus leapt from animals to humans. 

Patients with blood cancers such as leukaemia vary in their immune response to COVID-19 and can struggle to clear infection for very many weeks.

Researchers at the Crick, King’s College London and Guy's and St Thomas' NHS Foundation Trust, have found a common immune signature in the blood of patients with COVID-19, which could be used to predict how severely ill a patient will become, aiding patient management. 

Researchers at the Crick and Charité – Universitätsmedizin Berlin have identified 27 protein biomarkers that could be used to predict whether a patient with COVID-19 is likely to become severely ill with the disease.

Researchers at the Crick have identified a variant of the SARS-CoV-2 cell receptor ACE2, which is driven by antiviral interferon signals. The virus is not able to bind to this variant, dispelling concerns that interferon-based treatments could be inadvertently helping it spread more quickly in the body.

Researchers at the Crick have validated a method to test for SARS-CoV-2. The team have shared their protocols for using this promising method and how to report results to health authorities. 

UCLH and the Francis Crick Institute have formed a partnership to deliver a new large-scale COVID-19 vaccination centre at the institute.