Research case studies Explore a selection of reports that spotlight particular areas of research at the Crick over the past five years.
Postdoctoral clinical fellows Opportunities for postdoctoral clinicians to consolidate their research experience.
Search Results Fulltext search 719 Results Found Unlocking Pandora's box: personalising cancer cell death in non-small cell lung cancer Authors (2) Dean A FennellCharles Swanton EPMA Journal Published 1 January 2012 Crick labsCharles SwantonFull details Increase in cellular triacylglycerol content and emergence of large ER-associated lipid droplets in the absence of CDP-DG synthase function Authors (7) Yue He Candice Yam Kyle Pomraning Jacqueline SR Chin Joanne Y Yew Michael FreitagSnezhka Oliferenko Molecular Biology of the Cell Published 15 December 2014 Crick labsSnezhana OliferenkoFull details Robust polarity specification operates above a threshold of microtubule dynamicity Authors (3) Rahul Thadani Daniel HuangSnezhka Oliferenko Cytoskeleton Published 1 May 2011 Crick labsSnezhana OliferenkoFull details Molecular reconstruction of recurrent evolutionary switching in olfactory receptor specificity Authors (3)Lucia Prieto Godino Hayden R Schmidt Richard Benton eLife Published 22 October 2021 Crick labsLucia Prieto-GodinoFull details GEN1 promotes common fragile site expression Authors (7)Anaid BenitezMarie SebaldKanagaraj RadhakrishnanMonica Rodrigo BrenniYing Wai ChanEric Chih-Chao LiangStephen West Cell Reports Published 28 February 2023 Crick labs/ facilitiesStephen WestLight MicroscopyHigh Throughput ScreeningFlow CytometryAdvanced SequencingFull details Colorectal cancer progression: lessons from Drosophila? Authors (2) Graham P Bell Barry J Thompson Seminars in Cell & Developmental Biology Published 1 April 2014 Crick labsBarry ThompsonFull details Circadian rhythms in the absence of the clock gene Bmal1 Authors (7) Sandipan Ray Utham K Valekunja Alessandra Stangherlin Steven A HowellBram Snijders Gopinath Damodaran Akhilesh B Reddy Science Published 14 February 2020 Crick labs/ facilitiesProteomicsBioinformatics and BiostatisticsAdvanced SequencingFull details Polε instability drives replication stress, abnormal development, and tumorigenesis Authors (14)Roberto BellelliValerie Borel Clare Logan Jennifer Svendsen Danielle CoxEmma Nye[...] Helen R FlynnBram Snijders François Lassailly Andrew JacksonSimon Boulton Molecular Cell Published 17 May 2018 Crick labs/ facilitiesSimon BoultonProteomicsExperimental HistopathologyBiological Research FacilityFull details Delineating the rules for structural adaptation of membrane-associated proteins to evolutionary changes in membrane lipidome Authors (10)Maria Makarova Maria Peter Gabor Balogh Attila GlatzJames Macrae Nestor Lopez Mora Paula Booth Eugene Makeyev Laszlo VighSnezhka Oliferenko Current Biology Published 3 February 2020 Crick labs/ facilitiesSnezhana OliferenkoMetabolomicsStructural BiologyFull details The EMT transcription factor Snai1 maintains myocardial wall integrity by repressing intermediate filament gene expression Authors (8) Alessandra Gentile Anabela Bensimon-BritoRashmi Priya Hans-Martin Maischein Janett Piesker Stefan Guenther Felix Gunawan Didier YR Stainier eLife Published 21 June 2021 Crick labsRashmi PriyaFull details Pagination First page First Previous page Previous … Page 26 Page 27 Page 28 Page 29 Current page 30 Page 31 Page 32 Page 33 Page 34 … Next page Next Last page Last
Unlocking Pandora's box: personalising cancer cell death in non-small cell lung cancer Authors (2) Dean A FennellCharles Swanton EPMA Journal Published 1 January 2012 Crick labsCharles SwantonFull details
Increase in cellular triacylglycerol content and emergence of large ER-associated lipid droplets in the absence of CDP-DG synthase function Authors (7) Yue He Candice Yam Kyle Pomraning Jacqueline SR Chin Joanne Y Yew Michael FreitagSnezhka Oliferenko Molecular Biology of the Cell Published 15 December 2014 Crick labsSnezhana OliferenkoFull details
Robust polarity specification operates above a threshold of microtubule dynamicity Authors (3) Rahul Thadani Daniel HuangSnezhka Oliferenko Cytoskeleton Published 1 May 2011 Crick labsSnezhana OliferenkoFull details
Molecular reconstruction of recurrent evolutionary switching in olfactory receptor specificity Authors (3)Lucia Prieto Godino Hayden R Schmidt Richard Benton eLife Published 22 October 2021 Crick labsLucia Prieto-GodinoFull details
GEN1 promotes common fragile site expression Authors (7)Anaid BenitezMarie SebaldKanagaraj RadhakrishnanMonica Rodrigo BrenniYing Wai ChanEric Chih-Chao LiangStephen West Cell Reports Published 28 February 2023 Crick labs/ facilitiesStephen WestLight MicroscopyHigh Throughput ScreeningFlow CytometryAdvanced SequencingFull details
Colorectal cancer progression: lessons from Drosophila? Authors (2) Graham P Bell Barry J Thompson Seminars in Cell & Developmental Biology Published 1 April 2014 Crick labsBarry ThompsonFull details
Circadian rhythms in the absence of the clock gene Bmal1 Authors (7) Sandipan Ray Utham K Valekunja Alessandra Stangherlin Steven A HowellBram Snijders Gopinath Damodaran Akhilesh B Reddy Science Published 14 February 2020 Crick labs/ facilitiesProteomicsBioinformatics and BiostatisticsAdvanced SequencingFull details
Polε instability drives replication stress, abnormal development, and tumorigenesis Authors (14)Roberto BellelliValerie Borel Clare Logan Jennifer Svendsen Danielle CoxEmma Nye[...] Helen R FlynnBram Snijders François Lassailly Andrew JacksonSimon Boulton Molecular Cell Published 17 May 2018 Crick labs/ facilitiesSimon BoultonProteomicsExperimental HistopathologyBiological Research FacilityFull details
Delineating the rules for structural adaptation of membrane-associated proteins to evolutionary changes in membrane lipidome Authors (10)Maria Makarova Maria Peter Gabor Balogh Attila GlatzJames Macrae Nestor Lopez Mora Paula Booth Eugene Makeyev Laszlo VighSnezhka Oliferenko Current Biology Published 3 February 2020 Crick labs/ facilitiesSnezhana OliferenkoMetabolomicsStructural BiologyFull details
The EMT transcription factor Snai1 maintains myocardial wall integrity by repressing intermediate filament gene expression Authors (8) Alessandra Gentile Anabela Bensimon-BritoRashmi Priya Hans-Martin Maischein Janett Piesker Stefan Guenther Felix Gunawan Didier YR Stainier eLife Published 21 June 2021 Crick labsRashmi PriyaFull details