Research case studies Explore a selection of reports that spotlight particular areas of research at the Crick over the past five years.
Postdoctoral clinical fellows Opportunities for postdoctoral clinicians to consolidate their research experience.
Search Results Fulltext search 719 Results Found Tuning of in vivo cognate B-T cell interactions by Intersectin 2 is required for effective anti-viral B cell immunity Authors (9) Marianne BurbageFrancesca Gasparrini Shweta Aggarwal Mauro Gaya Johan Arnold Usha NairMichael Way Andreas Bruckbauer Facundo D Batista eLife Published 16 January 2018 Crick labs/ facilitiesMichael WayFlow CytometryBiological Research FacilityFull details The deubiquitinase USP28 controls intestinal homeostasis and promotes colorectal cancer Authors (9) Markus E Diefenbacher Nikita Popov Sophia M Blake Christina Schülein-VölkEmma Nye Bradley Spencer-Dene Laura A Jaenicke Martin EilersAxel Behrens Journal of Clinical Investigation Published 1 August 2014 Crick labs/ facilitiesAxel BehrensExperimental HistopathologyFull details Minor change, major difference: divergent functions of highly conserved cis-regulatory elements subsequent to whole genome duplication events Authors (5) DK Goode HA Callaway GA Cerda KE Lewis G Elgar Development Published 19 January 2011Full details Ssrp1a controls organogenesis by promoting cell cycle progression and RNA synthesis Authors (7) Katarzyna Koltowska Holger Apitz Despina Stamataki Elizabeth MA Hirst Heather VerkadeIris Salecker Elke A Ober Development Published 1 January 2013 Crick labs/ facilitiesIris SaleckerElectron MicroscopyFull details WASp-dependent actin cytoskeleton stability at the dendritic cell immunological synapse is required for extensive, functional T cell contacts Authors (10)Dessi Malinova Marco Fritzsche Carla R Nowosad Hannah Armer Peter MG Munro Michael P Blundell Guillaume CharrasPavel Tolar Gerben Bouma Adrian J Thrasher Journal of Leukocyte Biology Published 1 May 2016 Crick labsPavel TolarFull details Fission yeast MOZART1/Mzt1 is an essential γ-tubulin complex component required for complex recruitment to the microtubule organizing center, but not its assembly Authors (4) Hirohisa Masuda Risa Mori Masashi Yukawa Takashi Toda Molecular Biology of the Cell Published 1 September 2013Full details SCF ensures meiotic chromosome segregation through a resolution of meiotic recombination intermediates Authors (4) Shin-ya Okamoto Masamitsu Sato Takashi Toda Masayuki Yamamoto PLOS ONE Published 1 January 2012Full details HIV skews the lineage-defining transcriptional profile of Mycobacterium tuberculosis-specific CD4+ T cells Authors (8) Catherine Riou Natalie Strickland Andreia P Soares Björn Corleis Douglas S Kwon E John WherryRobert Wilkinson Wendy A Burgers Journal of Immunology Published 1 April 2016 Crick labsRobert J WilkinsonFull details Psychophysical properties of odor processing can be quantitatively described by relative action potential latency patterns in mitral and tufted cells Authors (2)Andreas Schaefer TW Margrie Frontiers in Systems Neuroscience Published 1 January 2012 Crick labsAndreas SchaeferFull details Geminin regulates cortical progenitor proliferation and differentiation Authors (9) M Spella C Kyrousi E Kritikou A StathopoulouFrancois Guillemot D KioussisVassilis Pachnis Z Lygerou S Taraviras Stem Cells Published 16 June 2011 Crick labsVassilis PachnisFrancois GuillemotFull details Pagination First page First Previous page Previous … Page 41 Page 42 Page 43 Page 44 Current page 45 Page 46 Page 47 Page 48 Page 49 … Next page Next Last page Last
Tuning of in vivo cognate B-T cell interactions by Intersectin 2 is required for effective anti-viral B cell immunity Authors (9) Marianne BurbageFrancesca Gasparrini Shweta Aggarwal Mauro Gaya Johan Arnold Usha NairMichael Way Andreas Bruckbauer Facundo D Batista eLife Published 16 January 2018 Crick labs/ facilitiesMichael WayFlow CytometryBiological Research FacilityFull details
The deubiquitinase USP28 controls intestinal homeostasis and promotes colorectal cancer Authors (9) Markus E Diefenbacher Nikita Popov Sophia M Blake Christina Schülein-VölkEmma Nye Bradley Spencer-Dene Laura A Jaenicke Martin EilersAxel Behrens Journal of Clinical Investigation Published 1 August 2014 Crick labs/ facilitiesAxel BehrensExperimental HistopathologyFull details
Minor change, major difference: divergent functions of highly conserved cis-regulatory elements subsequent to whole genome duplication events Authors (5) DK Goode HA Callaway GA Cerda KE Lewis G Elgar Development Published 19 January 2011Full details
Ssrp1a controls organogenesis by promoting cell cycle progression and RNA synthesis Authors (7) Katarzyna Koltowska Holger Apitz Despina Stamataki Elizabeth MA Hirst Heather VerkadeIris Salecker Elke A Ober Development Published 1 January 2013 Crick labs/ facilitiesIris SaleckerElectron MicroscopyFull details
WASp-dependent actin cytoskeleton stability at the dendritic cell immunological synapse is required for extensive, functional T cell contacts Authors (10)Dessi Malinova Marco Fritzsche Carla R Nowosad Hannah Armer Peter MG Munro Michael P Blundell Guillaume CharrasPavel Tolar Gerben Bouma Adrian J Thrasher Journal of Leukocyte Biology Published 1 May 2016 Crick labsPavel TolarFull details
Fission yeast MOZART1/Mzt1 is an essential γ-tubulin complex component required for complex recruitment to the microtubule organizing center, but not its assembly Authors (4) Hirohisa Masuda Risa Mori Masashi Yukawa Takashi Toda Molecular Biology of the Cell Published 1 September 2013Full details
SCF ensures meiotic chromosome segregation through a resolution of meiotic recombination intermediates Authors (4) Shin-ya Okamoto Masamitsu Sato Takashi Toda Masayuki Yamamoto PLOS ONE Published 1 January 2012Full details
HIV skews the lineage-defining transcriptional profile of Mycobacterium tuberculosis-specific CD4+ T cells Authors (8) Catherine Riou Natalie Strickland Andreia P Soares Björn Corleis Douglas S Kwon E John WherryRobert Wilkinson Wendy A Burgers Journal of Immunology Published 1 April 2016 Crick labsRobert J WilkinsonFull details
Psychophysical properties of odor processing can be quantitatively described by relative action potential latency patterns in mitral and tufted cells Authors (2)Andreas Schaefer TW Margrie Frontiers in Systems Neuroscience Published 1 January 2012 Crick labsAndreas SchaeferFull details
Geminin regulates cortical progenitor proliferation and differentiation Authors (9) M Spella C Kyrousi E Kritikou A StathopoulouFrancois Guillemot D KioussisVassilis Pachnis Z Lygerou S Taraviras Stem Cells Published 16 June 2011 Crick labsVassilis PachnisFrancois GuillemotFull details