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Resarch in the Turajlic lab on understanding the evolution of renal cell cancer.

A myriad of intriguing patterns exist throughout the natural world, many of which are visible to the naked eye.

Understanding how cells respond to ligands in complex physiological and pathological contexts in vivo requires a knowledge of the dynamics of signalling in addition to an understanding of the molecular wiring of the pathway. We have addressed this by using a combined experimental and computational modelling approach to study TGF-β superfamily signalling dynamics.

The Crick is wheelchair-accessible and can support visitors with disabilities.

Understanding mitotic nuclear remodeling from the comparative and synthetic biology perspectives is the main thrust of our current research.

Protein kinase C iota (PKCι) is a serine-threonine kinase that affects many cellular processes, including growth, proliferation, and motility.

Mammalian endonucleases play key roles in several DNA repair pathways and thereby help maintain genomic integrity.

In many cancers, only small subsets of cells are endowed with unlimited proliferative potential and are responsible for maintaining tumour growth, whereas the rest of the cells display a more differentiated phenotype and only have limited ability to proliferate.