Research case studies Explore a selection of reports that spotlight particular areas of research at the Crick over the past five years.
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Search Results Fulltext search 896 Results Found Looking forward to 2021 We asked people across the Crick to tell us about their bright spots of 2020 and their hopes for 2021. Published: 21 December 2020 Breadcrumb News & reports Charting DENR-dependent translation reinitiation uncovers predictive uORF features and links to circadian timekeeping via Clock Authors (6) Violeta Castelo-Szekely Mara De Matos Marina Tusup Steve PascoloJernej Ule David Gatfield Nucleic Acids Research Published 4 June 2019 Crick labsJernej UleFull details Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer Authors (87) Suzanne A Eccles Eric O Aboagye Simak Ali Annie S Anderson Jo Armes Fedor Berditchevski[...] Rosemary A Walker Christine J Watson Kaye J Williams Leonie S Young Alastair M Thompson Breast Cancer Research Published 1 January 2013 Crick labsErik SahaiFull details Tia1 dependent regulation of mRNA subcellular location and translation controls p53 expression in B cells Authors (6) Manuel D Díaz-Muñoz Vladimir Yu Kiselev Nicolas Le Novère Tomaz CurkJernej Ule Martin Turner Nature Communications Published 13 September 2017 Crick labsJernej UleFull details A developmentally regulated translational control pathway establishes the meiotic chromosome segregation pattern Authors (12) Luke E Berchowitz Aaron S GajadharFolkert Van Werven Alexandra A De Rosa Mariya L Samoylova Gloria A Brar[...] Che Xiao Bruce Futcher Jonathan S Weissman Forest M White Angelika Amon Genes & Development Published 1 October 2013 Crick labsFolkert van WervenFull details The key protein of endosomal mRNP transport Rrm4 binds translational landmark sites of cargo mRNAs Authors (9) Lilli Olgeiser Carl Haag Susan BoernerJernej Ule Anke Busch Janine Koepke Julian König Michael Feldbrügge Kathi Zarnack EMBO Reports Published 1 January 2019 Crick labsJernej UleFull details A genetically-encoded crosslinker screen identifies SERBP1 as a PKCε substrate influencing translation and cell division Authors (12)Silvia MartiniKhalil DavisRupert Faraway Lisa ElzeNicola LockwoodAndrew Jones[...]Neil McDonald David J Mann Alan ArmstrongJernej UlePeter Parker Nature Communications Published 26 November 2021 Crick labs/ facilitiesJernej UlePeter ParkerPaul NurseNeil McDonaldProteomicsLight MicroscopyFull details Translational readthrough of ciliopathy genes BBS2 and ALMS1 restores protein, ciliogenesis and function in patient fibroblasts Authors (4) Jonathan Eintracht Elizabeth Forsythe Helen May-SimeraMariya Moosajee EBioMedicine Published 1 August 2021 Crick labsMariya MoosajeeFull details Translating insights into tumor evolution to clinical practice: promises and challenges Authors (2)Matthew FittallPeter Van Loo Genome Medicine Published 29 March 2019 Crick labsPeter Van LooFull details Comparative genomics of cyclic-di-GMP signalling in bacteria: post-translational regulation and catalytic activity Authors (3) Aswin SN Seshasayee Gillian M FraserNicholas Luscombe Nucleic Acids Research Published 1 October 2010 Crick labsNicholas LuscombeFull details Pagination First page First Previous page Previous … Page 11 Page 12 Page 13 Page 14 Current page 15 Page 16 Page 17 Page 18 Page 19 … Next page Next Last page Last
Looking forward to 2021 We asked people across the Crick to tell us about their bright spots of 2020 and their hopes for 2021. Published: 21 December 2020 Breadcrumb News & reports
Charting DENR-dependent translation reinitiation uncovers predictive uORF features and links to circadian timekeeping via Clock Authors (6) Violeta Castelo-Szekely Mara De Matos Marina Tusup Steve PascoloJernej Ule David Gatfield Nucleic Acids Research Published 4 June 2019 Crick labsJernej UleFull details
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer Authors (87) Suzanne A Eccles Eric O Aboagye Simak Ali Annie S Anderson Jo Armes Fedor Berditchevski[...] Rosemary A Walker Christine J Watson Kaye J Williams Leonie S Young Alastair M Thompson Breast Cancer Research Published 1 January 2013 Crick labsErik SahaiFull details
Tia1 dependent regulation of mRNA subcellular location and translation controls p53 expression in B cells Authors (6) Manuel D Díaz-Muñoz Vladimir Yu Kiselev Nicolas Le Novère Tomaz CurkJernej Ule Martin Turner Nature Communications Published 13 September 2017 Crick labsJernej UleFull details
A developmentally regulated translational control pathway establishes the meiotic chromosome segregation pattern Authors (12) Luke E Berchowitz Aaron S GajadharFolkert Van Werven Alexandra A De Rosa Mariya L Samoylova Gloria A Brar[...] Che Xiao Bruce Futcher Jonathan S Weissman Forest M White Angelika Amon Genes & Development Published 1 October 2013 Crick labsFolkert van WervenFull details
The key protein of endosomal mRNP transport Rrm4 binds translational landmark sites of cargo mRNAs Authors (9) Lilli Olgeiser Carl Haag Susan BoernerJernej Ule Anke Busch Janine Koepke Julian König Michael Feldbrügge Kathi Zarnack EMBO Reports Published 1 January 2019 Crick labsJernej UleFull details
A genetically-encoded crosslinker screen identifies SERBP1 as a PKCε substrate influencing translation and cell division Authors (12)Silvia MartiniKhalil DavisRupert Faraway Lisa ElzeNicola LockwoodAndrew Jones[...]Neil McDonald David J Mann Alan ArmstrongJernej UlePeter Parker Nature Communications Published 26 November 2021 Crick labs/ facilitiesJernej UlePeter ParkerPaul NurseNeil McDonaldProteomicsLight MicroscopyFull details
Translational readthrough of ciliopathy genes BBS2 and ALMS1 restores protein, ciliogenesis and function in patient fibroblasts Authors (4) Jonathan Eintracht Elizabeth Forsythe Helen May-SimeraMariya Moosajee EBioMedicine Published 1 August 2021 Crick labsMariya MoosajeeFull details
Translating insights into tumor evolution to clinical practice: promises and challenges Authors (2)Matthew FittallPeter Van Loo Genome Medicine Published 29 March 2019 Crick labsPeter Van LooFull details
Comparative genomics of cyclic-di-GMP signalling in bacteria: post-translational regulation and catalytic activity Authors (3) Aswin SN Seshasayee Gillian M FraserNicholas Luscombe Nucleic Acids Research Published 1 October 2010 Crick labsNicholas LuscombeFull details