Research case studies Explore a selection of reports that spotlight particular areas of research at the Crick over the past five years.
Postdoctoral clinical fellows Opportunities for postdoctoral clinicians to consolidate their research experience.
Search Results Fulltext search 896 Results Found WDHD1 is essential for the survival of PTEN-inactive triple-negative breast cancer Authors (15) Ayse Ertay Huiquan Liu Dian Liu Ping Peng Charlotte Hill Hua Xiong[...]Michael Howell Paul Skipp Rob M EwingJulian Downward Yihua Wang Cell Death and Disease Published 21 November 2020 Crick labsJulian DownwardFull details The Xenopus ORFeome: a resource that enables functional genomics Authors (13) Ian M Grant Dawit Balcha Tong Hao Yun Shen Prasad Trivedi Ilya Patrushev[...] Limin Liu Aaron M Zorn P Todd Stukenberg David E Hill Michael J Gilchrist Developmental Biology Published 15 December 2015Full details G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo Authors (33) Roberto Simone Rubika Balendra Thomas G Moens Elisavet Preza Katherine M Wilson Amanda Heslegrave[...] Gary Parkinson Stephen NeidleRickie Patani Pietro Fratta Adrian M Isaacs EMBO Molecular Medicine Published 1 January 2018 Crick labsRickie PataniFull details USH2A-retinopathy: From genetics to therapeutics Authors (3)Lyes Toualbi Maria TomsMariya Moosajee Experimental Eye Research Published 1 December 2020 Crick labsMariya MoosajeeFull details Building gut from scratch - progress and update of intestinal tissue engineering Authors (4)Lucinda Tullie Brendan C Jones Paolo De CoppiVivian Li Nature Reviews Gastroenterology and Hepatology Published 1 July 2022 Crick labsVivian LiFull details Silver nanoparticles reduce brain inflammation and related neurotoxicity through induction of H2S-synthesizing enzymes Authors (12) Daniel A Gonzalez-Carter Bey Fen Leo Pakatip Ruenraroengsak Shu Chen Angela E Goode Ioannis G Theodorou[...]Raffaella Carzaniga Milo SP Shaffer David T Dexter Mary P Ryan Alexandra E Porter Scientific Reports Published 2 March 2017 Crick labs/ facilitiesElectron MicroscopyFull details Successful large gene augmentation of USH2A with non-viral episomal vectors Authors (5) Maria TomsLyes Toualbi Patrick V Almeida Richard HarbottleMariya Moosajee Molecular Therapy Published 6 September 2023 Crick labs/ facilitiesMariya MoosajeeBiological Research FacilityFull details Decoding the relationship between ageing and amyotrophic lateral sclerosis: a cellular perspective Authors (2)Viren PandyaRickie Patani Brain Published 1 April 2020 Crick labsRickie PataniFull details Enzymatic production of mono-ubiquitinated proteins for structural studies: the example of the Josephin domain of ataxin-3 Authors (8) Serena Faggiano Rajesh P MenonGeoff Kelly John McCormick Sokol V Todi K Matthew Scaglione Henry L Paulson Annalisa Pastore FEBS Open Bio Published 1 January 2013 Crick labs/ facilitiesMRC Biomedical NMR CentreMRC Biomedical NMR CentreFull details Analysis of the redox oscillations in the circadian clockwork Authors (6) Nikolay B Milev Guillaume Rey Utham K Valekunja Rachel S Edgar John S O'Neill Akhilesh B Reddy Methods in Enzymology Published 1 January 2015Full details Pagination First page First Previous page Previous … Page 53 Page 54 Page 55 Page 56 Current page 57 Page 58 Page 59 Page 60 Page 61 … Next page Next Last page Last
WDHD1 is essential for the survival of PTEN-inactive triple-negative breast cancer Authors (15) Ayse Ertay Huiquan Liu Dian Liu Ping Peng Charlotte Hill Hua Xiong[...]Michael Howell Paul Skipp Rob M EwingJulian Downward Yihua Wang Cell Death and Disease Published 21 November 2020 Crick labsJulian DownwardFull details
The Xenopus ORFeome: a resource that enables functional genomics Authors (13) Ian M Grant Dawit Balcha Tong Hao Yun Shen Prasad Trivedi Ilya Patrushev[...] Limin Liu Aaron M Zorn P Todd Stukenberg David E Hill Michael J Gilchrist Developmental Biology Published 15 December 2015Full details
G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo Authors (33) Roberto Simone Rubika Balendra Thomas G Moens Elisavet Preza Katherine M Wilson Amanda Heslegrave[...] Gary Parkinson Stephen NeidleRickie Patani Pietro Fratta Adrian M Isaacs EMBO Molecular Medicine Published 1 January 2018 Crick labsRickie PataniFull details
USH2A-retinopathy: From genetics to therapeutics Authors (3)Lyes Toualbi Maria TomsMariya Moosajee Experimental Eye Research Published 1 December 2020 Crick labsMariya MoosajeeFull details
Building gut from scratch - progress and update of intestinal tissue engineering Authors (4)Lucinda Tullie Brendan C Jones Paolo De CoppiVivian Li Nature Reviews Gastroenterology and Hepatology Published 1 July 2022 Crick labsVivian LiFull details
Silver nanoparticles reduce brain inflammation and related neurotoxicity through induction of H2S-synthesizing enzymes Authors (12) Daniel A Gonzalez-Carter Bey Fen Leo Pakatip Ruenraroengsak Shu Chen Angela E Goode Ioannis G Theodorou[...]Raffaella Carzaniga Milo SP Shaffer David T Dexter Mary P Ryan Alexandra E Porter Scientific Reports Published 2 March 2017 Crick labs/ facilitiesElectron MicroscopyFull details
Successful large gene augmentation of USH2A with non-viral episomal vectors Authors (5) Maria TomsLyes Toualbi Patrick V Almeida Richard HarbottleMariya Moosajee Molecular Therapy Published 6 September 2023 Crick labs/ facilitiesMariya MoosajeeBiological Research FacilityFull details
Decoding the relationship between ageing and amyotrophic lateral sclerosis: a cellular perspective Authors (2)Viren PandyaRickie Patani Brain Published 1 April 2020 Crick labsRickie PataniFull details
Enzymatic production of mono-ubiquitinated proteins for structural studies: the example of the Josephin domain of ataxin-3 Authors (8) Serena Faggiano Rajesh P MenonGeoff Kelly John McCormick Sokol V Todi K Matthew Scaglione Henry L Paulson Annalisa Pastore FEBS Open Bio Published 1 January 2013 Crick labs/ facilitiesMRC Biomedical NMR CentreMRC Biomedical NMR CentreFull details
Analysis of the redox oscillations in the circadian clockwork Authors (6) Nikolay B Milev Guillaume Rey Utham K Valekunja Rachel S Edgar John S O'Neill Akhilesh B Reddy Methods in Enzymology Published 1 January 2015Full details