Research case studies Explore a selection of reports that spotlight particular areas of research at the Crick over the past five years.
Postdoctoral clinical fellows Opportunities for postdoctoral clinicians to consolidate their research experience.
Search Results Fulltext search 895 Results Found Protein lipidation in cancer: mechanisms, dysregulation and emerging drug targets Authors (5) Edward W Tate Lior Soday Ana Losada de la Lastra Mei Wang Hening Lin Nature Reviews Cancer Published 1 April 2024 Crick labsEd TateFull details Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase Authors (21)Saz BasuTiffany MakRachel UlfertsMary Wu Tom Deegan Ryo Fujisawa[...]Rupert Beale Victoria H CowlingMichael Howell Karim LabibJohn Diffley Biochemical Journal Published 16 July 2021 Crick labs/ facilitiesPaul NurseJohn DiffleyRupert BealeHigh Throughput ScreeningFull details RGS4 RNA secondary structure mediates staufen2 RNP assembly in neurons Authors (11) Sandra M Fernández-Moya Janina Ehses Karl E Bauer Rico SchieweckAnob ChakrabartiFlora Lee Christin IlligNicholas Luscombe Max HarnerJernej Ule Michael A Kiebler International Journal of Molecular Sciences Published 1 December 2021 Crick labsJernej UleNicholas LuscombeFull details Sexual dimorphism in chronic hepatitis B virus (HBV) infection: Evidence to inform elimination efforts Authors (3) Robin Brown Philip GoulderPhilippa Matthews Wellcome Open Research Published 11 May 2022 Crick labsPhilippa MatthewsFull details Sexual dimorphism in chronic hepatitis B virus (HBV) infection: Evidence to inform elimination efforts Authors (3) Robin Brown Philip GoulderPhilippa Matthews Wellcome Open Research Published 26 April 2022 Crick labsPhilippa MatthewsFull details Assessing and enhancing migration of human myogenic progenitors using directed iPS cell differentiation and advanced tissue modelling Authors (10) SungWoo Choi Giulia Ferrari Louise A Moyle Kirsty Mackinlay Naira Naouar Salma Jalal Sara Benedetti Christine Wells Francesco MuntoniFrancesco Saverio Tedesco EMBO Molecular Medicine Published 10 October 2022 Crick labs/ facilitiesFrancesco Saverio TedescoLight MicroscopyFull details Multi-isotope imaging mass spectrometry quantifies stem cell division and metabolism Authors (8) ML SteinhauserAndrew Bailey SE Senyo C Guillermier TS PerlsteinAlex Gould RT Lee CP Lechene Nature Published 15 January 2012 Crick labsAlex GouldFull details Prognostic and predictive biomarkers in resected colon cancer: current status and future perspectives for integrating genomics into biomarker discovery Authors (21) Sabine Tejpar Monica Bertagnolli Fred Bosman Heinz-Joseph Lenz Levi Garraway Frederic Waldman[...] Ian Tomlinson Mauro Delorenzi Roberto Fiocca Eric Van Cutsem Arnaud Roth Oncologist Published 1 January 2010 Crick labsCharles SwantonFull details Xenografted human microglia display diverse transcriptomic states in response to Alzheimer's disease-related amyloid-β pathology Authors (17) Renzo Mancuso Nicola Fattorelli Anna Martinez-MurianaEmma Davis Leen Wolfs Johanna Van Den Daele[...] Suresh Poovathingal Sriram Balusu Catherine Verfaillie Mark FiersBart De Strooper Nature Neuroscience Published 27 March 2024 Crick labsBart de Strooper | Lorena ArancibiaFull details Mechanisms of hypoxia signalling: new implications for nephrology Authors (2) Johannes SchödelPeter Ratcliffe Nature Reviews Nephrology Published 1 October 2019 Crick labsPeter RatcliffeFull details Pagination First page First Previous page Previous … Page 57 Page 58 Page 59 Page 60 Current page 61 Page 62 Page 63 Page 64 Page 65 … Next page Next Last page Last
Protein lipidation in cancer: mechanisms, dysregulation and emerging drug targets Authors (5) Edward W Tate Lior Soday Ana Losada de la Lastra Mei Wang Hening Lin Nature Reviews Cancer Published 1 April 2024 Crick labsEd TateFull details
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase Authors (21)Saz BasuTiffany MakRachel UlfertsMary Wu Tom Deegan Ryo Fujisawa[...]Rupert Beale Victoria H CowlingMichael Howell Karim LabibJohn Diffley Biochemical Journal Published 16 July 2021 Crick labs/ facilitiesPaul NurseJohn DiffleyRupert BealeHigh Throughput ScreeningFull details
RGS4 RNA secondary structure mediates staufen2 RNP assembly in neurons Authors (11) Sandra M Fernández-Moya Janina Ehses Karl E Bauer Rico SchieweckAnob ChakrabartiFlora Lee Christin IlligNicholas Luscombe Max HarnerJernej Ule Michael A Kiebler International Journal of Molecular Sciences Published 1 December 2021 Crick labsJernej UleNicholas LuscombeFull details
Sexual dimorphism in chronic hepatitis B virus (HBV) infection: Evidence to inform elimination efforts Authors (3) Robin Brown Philip GoulderPhilippa Matthews Wellcome Open Research Published 11 May 2022 Crick labsPhilippa MatthewsFull details
Sexual dimorphism in chronic hepatitis B virus (HBV) infection: Evidence to inform elimination efforts Authors (3) Robin Brown Philip GoulderPhilippa Matthews Wellcome Open Research Published 26 April 2022 Crick labsPhilippa MatthewsFull details
Assessing and enhancing migration of human myogenic progenitors using directed iPS cell differentiation and advanced tissue modelling Authors (10) SungWoo Choi Giulia Ferrari Louise A Moyle Kirsty Mackinlay Naira Naouar Salma Jalal Sara Benedetti Christine Wells Francesco MuntoniFrancesco Saverio Tedesco EMBO Molecular Medicine Published 10 October 2022 Crick labs/ facilitiesFrancesco Saverio TedescoLight MicroscopyFull details
Multi-isotope imaging mass spectrometry quantifies stem cell division and metabolism Authors (8) ML SteinhauserAndrew Bailey SE Senyo C Guillermier TS PerlsteinAlex Gould RT Lee CP Lechene Nature Published 15 January 2012 Crick labsAlex GouldFull details
Prognostic and predictive biomarkers in resected colon cancer: current status and future perspectives for integrating genomics into biomarker discovery Authors (21) Sabine Tejpar Monica Bertagnolli Fred Bosman Heinz-Joseph Lenz Levi Garraway Frederic Waldman[...] Ian Tomlinson Mauro Delorenzi Roberto Fiocca Eric Van Cutsem Arnaud Roth Oncologist Published 1 January 2010 Crick labsCharles SwantonFull details
Xenografted human microglia display diverse transcriptomic states in response to Alzheimer's disease-related amyloid-β pathology Authors (17) Renzo Mancuso Nicola Fattorelli Anna Martinez-MurianaEmma Davis Leen Wolfs Johanna Van Den Daele[...] Suresh Poovathingal Sriram Balusu Catherine Verfaillie Mark FiersBart De Strooper Nature Neuroscience Published 27 March 2024 Crick labsBart de Strooper | Lorena ArancibiaFull details
Mechanisms of hypoxia signalling: new implications for nephrology Authors (2) Johannes SchödelPeter Ratcliffe Nature Reviews Nephrology Published 1 October 2019 Crick labsPeter RatcliffeFull details