4th Crick International Cancer Conference

Event date: 8 October 2023 - 10 October 2023
Start time: 09:00 End time: - 18:00
Event Location: The Francis Crick Institute
Event Type: Symposia

The 4th Crick International Cancer Conference will bring together world-leading experts in cancer research and offer many opportunities for in-person networking and engagement.

Draft programme

DAY 1 – Sunday 8th October

13:30
Registration and coffee
14:15
Opening remarks by scientific organisers
Session 1
Cancer as an aberrant tissue
14:20
Jacco van Rheenen | Netherlands Cancer Institute
"Filming the fate of cells that carry mutations in cancer driver genes"
14:50
Valerie Weaver | University of California San Francisco
"Inflammation forces tumor progression and metastasis"
15:20
Short talk 1 | Bartomeu Colom | Altos Labs
"Multiple mutant clones contribute to epithelial tumour initiation"
15:35
Sponsor talk from Navinci Diagnostics
15:40
Coffee break
16:10
James DeGregori | University of Colorado Anschutz Medical Campus
“Somatic evolution – causes and consequences”
16:40
Eduard Batlle | IRB Barcelona
"Stem cells, immune evasion and metastasis in colorectal cancer"
17:10
Short talk 2 | Catherine Hogan | ECSCRI, Cardiff University
"KRAS mutant cells override cell competition in adult pancreas via cell dormancy and Wnt"
17:25
Meet-the-speakers session 1 and networking drinks
18:45
End of day one

DAY 2 – Monday 9th October

08:30
Registration and coffee
Session 2
Cancer and the immune system
09:00
Caetano Reis e Sousa | The Francis Crick Institute
"Dendritic cells in immunity to cancer"
09:30
Yifat Merbl | Weizmann Institute, Rehovot
"Insights into proteasomal degradation in cancer"
10:00
Short talk 3 | Federica Lorenzi | ICR & the Francis Crick Institute
"ATRX aberrations mediate an immunogenic phenotype in neuroblastoma"
10:15
Sponsor talk from Automata
10:20
Coffee break
10:45
Daniela Thommen | Netherlands Cancer Institute
"Decoding and rewiring tumor-specific T cell immunity in human cancer tissue"
11:15
Short talk 4 | Oriol Pich | The Francis Crick Institute
"Clinical Implications of Clonal Hematopoiesis in the Tumor Microenvironment of Non-Small Cell Lung Cancer"
11:30
Flash talks 1
Marcos Burger Ramos | Barts Cancer Institute
Lies van Baarle | KU Leuven
Roberto Vendramin | UCL Cancer Institute & the Francis Crick Institute
Gillian Morrison | University of Edinburgh
Christos Ermogenous | Barts Cancer Institute
Pedro Victori | UCL Cancer Institute
Sasha Bailey | The Francis Crick Institute
May Zaw Thin | The Institute of Cancer Research
Nicola Nguyen | UCL
Oscar Maiques | Barts Cancer Institute
Nina Moderau | Imperial College London
12:00
Lunch break
Session 3
Understanding cancer trajectories
13:15
Serena Nik-Zainal | CRUK Cambridge Centre
13:45
Nuria Lopez-Bigas | IRB Barcelona
"Somatic mutations in tumors and normal tissues"
14:15
Short talk 5 | Alejandra Bruna | The ICR
"Investigating Adaptive phenotypic plasticity as an early cancer evolutionary driver in paediatric solid cancers for improved treatment strategies"
14:30
Short talk 6 | Omar Khan | Hamad Bin Khalifa University
"Control of TGFb signalling by ubiquitination independent function of E3 ubiquitin ligase TRIP12"
14:45
Sponsor talk from Lunaphore
14:50
Coffee break
15:15
Trevor Graham | The Institute of Cancer Research
15:45
Short talk 7 | Hendrik Messal | Netherlands Cancer Institute
"Mammary epithelial architecture modulates field cancerization"
16:00
Poster session 1, meet-the-speakers session 2 & 3 and networking drinks
18:00
End of day two

DAY 3 – Tuesday 10th October

08:30
Coffee & tea
Session 4
TME and metastasis
09:00
Sara Zanivan | CRUK Scotland Institute
"Harnessing CAF metabolism to establish an anti-tumour stroma"
09:30
Adrienne Boire | Memorial Sloan Kettering Cancer Center
10:00
Short talk 8 | Cassie Clarke | CRUK Beatson Institute
"Pyrimidine metabolism influences neutrophil behaviour to prime the metastatic microenvironment"
10:15
Sponsor talk from CancerTools.org
10:20
Coffee break
10:40
Mara Sherman | Memorial Sloan Kettering Cancer Center
"Mechanisms and consequences of pancreatic cancer stromal evolution"
11:10
Short talk 9 | Mirjana Efremova | Barts Cancer Institute
"Dissecting cellular heterogeneity and metastatic plasticity in colorectal cancer"
11:25
Flash talks 2
Kanish Mirchia | UCSF
Nuray Gunduz | CRUK Beatson Institute
Frances Pearl | University of Sussex
Charles Williams | University of Edinburgh
Sophie Munnings-Tomes | Institute of Child Health, UCL
Abigail Elliot | The University of Edinburgh
Nicola Calonaci | University of Trieste
Ilaria Marrocco | Catholic University of the Sacred Heart
James Black | The Francis Crick Institute & UCL
Elizabeth Lieschke | The Francis Crick Institute
(virtually) Naila Adam | The University of British Columbia
12:05
Lunch break
12:45
Poster session 2
Session 5
New therapeutic approaches
14:00
Daniel Peeper | Netherlands Cancer Institute
"Function-based genomics to combat immunotherapy resistance"
14:30
Bart Vanhaesebroeck | UCL Cancer Institute
"In search of novel ways to modulate the PI3K pathway for therapeutic benefit"
15:00
Short talk 10 | Alexis Barr | MRC-LMS
"CDK4/6 inhibitor-mediated cell overgrowth triggers an osmotic stress response and chronic p38-p53-p21 activation to promote long-term cell cycle withdrawal"
15:15
Coffee break & Meet the speaker session 4 & 5
15:45
Laura Soucek | Vall d'Hebron Institute of Oncology
"Joys and pains of developing the first clinically viable MYC inhibitor"
16:15
Short talk 11 | Giorgio Galli | Novartis Institute for Biomedical Research
"Large scale functional genomics screens inform cancer lineage-specific therapeutic interventions in Hippo-YAP pathway"
16:30
Prizes (best flash talk, best selected abstract talk, best poster)
Concluding remarks by scientific organisers