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Crick Cancer Research Symposium

Event date: 5 October 2020 - 6 October 2020
Start time: 09:00 End time: - 17:00
Event Location: The Francis Crick Institute
Event Type: Symposia

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This two-day biennial symposium which alternates with the larger Crick Cancer Conference will include a keynote from Fiona Watt, FRS FMedSci, alongside a full programme of invited speaker talks,selected short talks and lunchtime workshops run by some of our sponsors.

Due to ongoing social distancing measures, we will run this symposium as a "hybrid" event with a limited number of Crick only places in the auditorium alongside virtual attendees. You will need to register via eventbrite for this symposium and will then receive your zoom invitation.

Poster sessions will take place on a virtual poster gallery and we encourage people to submit their abstracts for short and flash talks and posters.

Please submit your abstract using the attached form to events@crick.ac.uk by September 7th 2020

Programme

10:30
Welcome and opening remarks | Erik Sahai - Francis Crick Institute
Session 1
Cancer invasion and metastasis
10:35
Nicola Aceto | University of Basel |"Biology and vulnerabilities of circulating tumour cells"
11:05
Fabiana Lüönd | University of Basel|Short talk 1-"Lineage Tracing Reveals Distinct Contributions of Partial and Full Epithelial-Mesenchymal Transition to Breast Cancer Metastasis and Chemoresistance"
11:20
Clare Isacke | Institute of Cancer Research | " Targeting the tumour microenvironment"
11:50
Jinwook Choi|University of Cambridge|Short talk 2-"Kras^G12D drives cellular heterogeneity in lung tumour progression by recapitulating alveolar regeneration occurring during injury repair. "
12:05
Simona Parinello | UCL Cancer Institute | "Microenvironmental control of glioblastoma invasion"
12:35
Lunch break, posters and sponsor workshops
12:45 - 13:05
Sponsor workshop 1 - Miltenyi Biotec Limited
13:20 - 13:40
Sponsor workshop 2 - MedChem Express
Session 2
Cancer, stroma and the immune system
14:00
Dinis Calado | Francis Crick Institute | "MYC, Cancer Phenotypes and Dependencies "
14:30
Florian Bock|CRUK Beatson Institute| talk 3-"What doesn’t kill you makes your neighbour stronger: paracrine resistance to chemotherapy"
14:45
Jacqui Shields | MRC Cancer Unit | "Beyond the cancer cell: exploring the tumour stroma as immune modulators"
15:15
Break
15:30
Santiago Zelenay | Cancer Research UK Manchester Institute | ‘Manipulating inflammation to raise cancer immunogenicity.’
16:00
Reda Keddar|Francis Crick Institute|Short talk 4-"Immunogenomics of colorectal cancer response to immune checkpoint blockade"
Keynote
16:15
Keynote Fiona Watt | MRC | ‘Leaving the Epidermal Stem Cell Compartment’
17:00
End of the day. poster session and networking over slack.

Session 3
Gene and metabolic networks in Cancer
10:00
Marc Mansour | UCL Cancer Institute | "Somatically acquired PRC2 mutations induce epigenetic reprogramming and an exploitable dependency on the replication stress checkpoint in T-cell acute lymphoblastic leukaemia"
10:30
Maria Glymenaki | Imperial college London | Short talk 5 - "Biogenic amines – a potential factor for increased colon cancer risk following bariatric surgery"
10:45
George Poulogiannis | Institute of Cancer Research | "Harnessing metabolism for the diagnosis and treatment of mutant PIK3CA-bearing cancers"
11:15
Break
11:30
Sebastiaan Vanuytven | KU Leuven | Short talk 6 - "Single-cell Genome-and-Transcriptome sequencing without upfront whole-genome amplification reveals cell state plasticity of melanoma subclones"
11:45
Jasmin Fisher | UCL Cancer Institute | Translational application of computational models for patient benefit”
12:15
Lunch break, posters and sponsor workshops
12:30 - 12:50
Sponsor workshop 1 - Sartorius AG
13:00 - 13:20
Sponsor workshop 2 - Mettler Toledo
Session 4
Cancer heterogeneity and evolution
13:30
Luca Magnani | Imperial College London |“The role of genetic and non genetic heterogeneity in hormone dependent breast cancers”
14:00
Ioannis Loukas | The Francis Crick Institute | Short talk 7 - "Epigenetic deregulation enhances cancer cell plasticity and adaptability to environmental challenges"
14:15
Eugenia Piddini | University of Bristol | “Mechanical Cell Competition: mechanisms and implications for tumorigenesis”
14:45
Sara Badodi | Queen Mary University of London | Short talk 8 - "Inositol treatment inhibits medulloblastoma through suppression of epigenetic-driven metabolic adaptation."
15:00
Break
15:15
Tariq Enver | UCL | "Origin, evolution and targeting of childhood leukaemia"
15:45
Paola Scaffidi/Ilaria Malanchi | Francis Crick Institute | Closing remarks

Speakers

Fiona

Fiona Watt - Keynote

MRC
London, UK

Nicola A

Nicola Aceto

University of Basel
Basel, Switzerland

dinis c

Dinis Calado

The Francis Crick Institute
London, UK

Tariq Enver

Tariq Enver

UCL
London, UK

Clare Isacke

Clare Isacke

ICR
London, UK

Luca Magnani

Luca Magnani

Imperial College London
London, UK

Marc

Marc Mansour

UCLH
London, UK

Simona Land

Simona Parrinello

UCL Cancer Institute.

Eugenia

Eugenia Piddini

University of Bristol
Bristol, UK

George Poulogiannis

ICR
London, UK

Jasmin Fisher

Jasmin Fisher

UCL London, UK

Jacqui Shields

Jacqui Shields

MRC Cancer Unit
London, UK

Zel

Santiago Zelenay

CRUK Manchester
Manchester, UK

Hosts

Erik Sahai

Principal Group Leader - Assistant Research Director

Lab: Tumour Cell Biology LaboratoryLead, Team member

Ilaria Malanchi

Principal Group Leader

Lab: Tumour-Host Interaction LaboratoryLead, Team member

Paola Scaffidi

Visiting Scientist

Lab: Cancer Epigenetics LaboratoryLead, Team member

Sponsors

medchem

Miltenyi biotec

Miltenyi Biotec

Sartorius

Mettler