Title: Ubitquitin-dependant control of cell signalling
Katrin Rittinger is a Senior Group Leader here at the Crick. Her lab, the Molecular Structure of Cell Signalling Laboratory, studies communication within the cell, how it responds to changes to its environment and what goes wrong in disease.
Katrin Rittinger obtained a degree in chemistry from the University of Heidelberg, Germany. She then went on to do a PhD at the Max Planck Institute for Medical Research in Heidelberg in the group of Roger Goody, characterising the nucleotide and oligonucleotide-binding properties of HIV reverse transcriptase and the mechanism of action of non-nucleoside RT inhibitors.
After a short postdoctoral period at the Max Planck Institute for Molecular Physiology in Dortmund, Germany, she came to the Medical Research Council National Institute for Medical Research (now part of the Francis Crick Institute) in 1996 for a second postdoc, working on the structural characterisation of 14-3-3/ligand complexes and the regulation of Rho family GTPases.
In 2000, she established her own research group and has since studied a number of multi-protein assemblies that regulate different aspects of signal transduction using biochemical and structural methods.