Peter Carmeliet: Angiogenesis revisited: role and (therapeutic) implications of endothelial metabolism
Peter Carmeliet is Adjunct Director of the VIB Vesalius Research Centre at the Catholic University of Leuven, Belgium. Notably, in 2016, he identified neuron-producing stem cells in the brain.
His laboratory focuses on Angiogenesis; the growth of new blood vessels in health and disease. Abnormal blood vessel growth, excessive or insufficient, contributes to multiple disorders, including cardiovascular disease, diabetes, cancer, age-related blindness and stroke. The aim of Carmeliet's lab is to develop therapeutic concepts and, if possible, innovative anti-angiogenic treatments.
The Carmeliet lab is also interested in unraveling the molecular basis of EC (endothelial cell) dysfunction and EC regeneration. EC dysfunction is important in diseases such as diabetes and metabolic syndrome. It is a key determinant of cardiovascular morbidity and mortality, even when glycemia levels are under control.
Carmeliet has won various awards, including the Francqui Prize in Biological and Medical Sciences (2002) Interbrew-Baillet Latour Health Prize (2005) and Ernst Jung Prize in Medicine (2010). He was was elected a foreign member of the Royal Netherlands Academy of Arts and Sciences in 2017.