Seminar in the Crick's auditorium.

: Medicine at the Crick | How can therapeutics target cancer stem cells?

  • Event Status: Book now : Event date:
  • Start time: 14:00 End time: - 17:40
  • Event Location: The Francis Crick Institute
  • Event Type: Seminar
 Our ninth Medicine at the Crick event will be hosted by Professor Dominique Bonnet of the Francis Crick Institute.

Tumour heterogeneity represents an ongoing challenge in the field of cancer therapy. Heterogeneity is evident between cancers from different patients and within a single tumour. The latter includes phenotypic diversity such as cell surface markers, (epi)genetic abnormality, growth rate, apoptosis and other hallmarks of cancer that eventually drive disease progression and treatment failure. Cancer stem cells (CSCs) have been put forward to be one of the non-genetic determining factors that contribute to intra-tumour heterogeneity.

In this ninth edition of Medicine at the Crick, we will review our current understanding of cancer stem cells, their role in initiation, progression and chemoresistance. We will also discuss new therapeutic avenues to eradicate these cells.

We plan to hold this as a hybrid event with a limited in person audience alongside online attendees.

Register on EventBrite and full joining details for all attendees will be sent in advance of the event.


Confirmed speakers

Axel Behrens

 Axel Behrens Scientific Director, CRUK Convergence Science Centre

 Institute of Cancer Research and Imperial College London


John Dick

 John E. Dick PhD FRS Canada Research Chair in Stem Cell Biology

Senior Scientist, Princess Margaret Cancer Centre, University Health Network

Professor- Department of Molecular Genetics, University of Toronto


Simona Parinello

 Simona Parrinello Professor of Neuro-oncology &Co-lead of the UCL Cancer Research UK Brain Tumour Centre of Excellence

Department of Cancer Biology, UCL Cancer Institute

Jeremy Rich

Jeremy N. Rich, MD, MHS, MBA  Deputy Director for Research, UPMC Hillman Cancer Center

Pittsburgh Foundation Chair in Personalized Cancer Therapies

Professor, Department of Neurology 


Dominique Bonnet

 Professor Dominique Bonnet The Francis Crick Institute