Image of the front of the Crick with a tree in shot.

Medicine at the Crick | RNA Epitranscriptomics in Health and Disease

Medicine at the Crick event series

These events showcase major advances in biomedical science.

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This 22nd edition of Medicine at the Crick will be hosted by Folkert van Werven (The Francis Crick Institute). 

The epitranscriptome is a layer of chemical modifications or tags on RNAs that controls how cells read genetic instructions without changing our underlying DNA. When these tags work properly, they keep our bodies healthy. Scientists have harnessed them to make life-saving therapies, like the modified building blocks in mRNA vaccines that prevent our immune system from destroying the vaccine before it works. When these tags malfunction, they can drive diseases like cancer by helping tumour growth and resisting treatment. Today, researchers are developing targeted drugs that block the specific enzymes controlling these RNA tags, offering a powerful new way to treat disease. 

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